PURPOSE: The present investigation clinically and histologically evaluated the use of fresh-frozen bone in the reconstruction of maxillary alveolar ridges to confirm the effective bone fill and support for the placement of dental implants. PATIENTS AND METHODS: Fifteen patients who had atrophic maxillary ridge necessitating bone block grafts prior to implant placement were submitted to maxillary reconstructions performed with human block grafts of tibia fresh-frozen chips. Nine months later the re-entry procedures were carried out and at this time a bone core was removed from the grafts for histological analysis. RESULTS: Thirty-four blocks were placed, and the number of blocks each patient received ranged from 1 to 4. During the re-entry procedures, all of the grafts were found to be firm in consistency, well-incorporated, and vascularized. A total of 51 implants were placed over the grafts with a minimum of 40-Newton torque in all cases. None of the implants were lost. The follow-up period ranged from 24 to 35 months. The histological analysis revealed a living bone that showed features characteristic of mature and compact osseous tissue surrounded by marrow spaces. CONCLUSION: Bone allografts can be successful as graft material for the treatment of maxillary ridge defects. If adequate surgical techniques are adopted, this type of bone graft can be safely used in regions of implant placement as a suitable alternative to autogenous grafts.
PURPOSE: The present investigation clinically and histologically evaluated the use of fresh-frozen bone in the reconstruction of maxillary alveolar ridges to confirm the effective bone fill and support for the placement of dental implants. PATIENTS AND METHODS: Fifteen patients who had atrophic maxillary ridge necessitating bone block grafts prior to implant placement were submitted to maxillary reconstructions performed with human block grafts of tibia fresh-frozen chips. Nine months later the re-entry procedures were carried out and at this time a bone core was removed from the grafts for histological analysis. RESULTS: Thirty-four blocks were placed, and the number of blocks each patient received ranged from 1 to 4. During the re-entry procedures, all of the grafts were found to be firm in consistency, well-incorporated, and vascularized. A total of 51 implants were placed over the grafts with a minimum of 40-Newton torque in all cases. None of the implants were lost. The follow-up period ranged from 24 to 35 months. The histological analysis revealed a living bone that showed features characteristic of mature and compact osseous tissue surrounded by marrow spaces. CONCLUSION: Bone allografts can be successful as graft material for the treatment of maxillary ridge defects. If adequate surgical techniques are adopted, this type of bone graft can be safely used in regions of implant placement as a suitable alternative to autogenous grafts.
Authors: Marta Krasny; Kornel Krasny; Artur Kamiński; Małgorzata Zadurska; Piotr Piekarczyk; Piotr Fiedor Journal: Cell Tissue Bank Date: 2012-12-13 Impact factor: 1.522
Authors: Eugénio Pereira; Ana Messias; Ricardo Dias; Fernando Judas; Alexander Salvoni; Fernando Guerra Journal: Clin Implant Dent Relat Res Date: 2014-10-27 Impact factor: 3.932
Authors: F S De Ponte; G Cutroneo; R Falzea; G Rizzo; L Catalfamo; A Favaloro; G Vermiglio; M Runci; A Centofanti; G Anastasi Journal: Eur J Histochem Date: 2016-12-06 Impact factor: 3.188
Authors: Alberto Monje; Michael A Pikos; Hsun-Liang Chan; Fernando Suarez; Jordi Gargallo-Albiol; Federico Hernández-Alfaro; Pablo Galindo-Moreno; Hom-Lay Wang Journal: Biomed Res Int Date: 2014-09-11 Impact factor: 3.411