Literature DB >> 19445541

The correlation between GPR30 and clinicopathologic variables in breast carcinomas.

G Tu1, D Hu, G Yang, T Yu.   

Abstract

The G-protein-coupled-receptor 30 (GPR30) is a new membrane estrogen receptor. The aim of the present study was to determine the correlations among GPR30, ERalpha, PR, C-erbB-2, p53, TNM stage, and pathologic grade in breast carcinomas. Two hundred forty-one biopsy specimens were evaluated with immunohistochemical assays, and then correlations were analyzed. Low negative correlations of GPR30 with ERalpha (r = -0.144, P<0.05) and PR (r = -0.214, P<0.01) were observed. Associations of GPR30 with C-erbB-2, p53, TNM stage, and pathologic grade were not confirmed. These findings indicated that GPR30 might be an independent prognostic factor in breast carcinomas.

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Year:  2009        PMID： 19445541     DOI： 10.1177/153303460900800308

Source DB:  PubMed          Journal:  Technol Cancer Res Treat        ISSN： 1533-0338


  9 in total

1.  GPER functions as a tumor suppressor in triple-negative breast cancer cells.

Authors:  Christine Weißenborn; Tanja Ignatov; Hans-Joachim Ochel; Serban Dan Costa; Ana Claudia Zenclussen; Zoya Ignatova; Atanas Ignatov
Journal:  J Cancer Res Clin Oncol       Date:  2014-02-20       Impact factor: 4.553

2.  GPER functions as a tumor suppressor in MCF-7 and SK-BR-3 breast cancer cells.

Authors:  Christine Weißenborn; Tanja Ignatov; Angela Poehlmann; Anja K Wege; Serban D Costa; Ana Claudia Zenclussen; Atanas Ignatov
Journal:  J Cancer Res Clin Oncol       Date:  2014-02-11       Impact factor: 4.553

3.  G protein-coupled estrogen receptor (GPER) mediates NSCLC progression induced by 17β-estradiol (E2) and selective agonist G1.

Authors:  Changyu Liu; Yongde Liao; Sheng Fan; Hexiao Tang; Zhixiao Jiang; Bo Zhou; Jing Xiong; Sheng Zhou; Man Zou; Jianmiao Wang
Journal:  Med Oncol       Date:  2015-03-06       Impact factor: 3.064

Review 4.  The G-protein-coupled estrogen receptor GPER in health and disease.

Authors:  Eric R Prossnitz; Matthias Barton
Journal:  Nat Rev Endocrinol       Date:  2011-08-16       Impact factor: 43.330

Review 5.  Rewiring of the Endocrine Network in Triple-Negative Breast Cancer.

Authors:  Kaixuan Li; Dongjiang Zong; Jianrong Sun; Danxiang Chen; Minkai Ma; Liqun Jia
Journal:  Front Oncol       Date:  2022-06-30       Impact factor: 5.738

6.  Proliferation and apoptosis regulation by G protein-coupled estrogen receptor in glioblastoma C6 cells.

Authors:  Coral Estefania Gutiérrez-Almeida; Anne Santerre; Lilia Carolina León-Moreno; Irene Guadalupe Aguilar-García; Rolando Castañeda-Arellano; Sergio Horacio Dueñas-Jiménez; Judith Marcela Dueñas-Jiménez
Journal:  Oncol Lett       Date:  2022-05-18       Impact factor: 3.111

7.  Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer.

Authors:  Venkatakrishna Rao Jala; Brandie N Radde; Bodduluri Haribabu; Carolyn M Klinge
Journal:  BMC Cancer       Date:  2012-12-28       Impact factor: 4.430

8.  G-protein Coupled Estrogen Receptor 1 Expression in Primary Breast Cancers and Its Correlation with Clinicopathological Variables.

Authors:  Hao-Jun Luo; Ping Luo; Guang-Lun Yang; Qiong-le Peng; Man-Ran Liu; Gang Tu
Journal:  J Breast Cancer       Date:  2011-09-29       Impact factor: 3.588

9.  GPER-mediated proliferation and estradiol production in breast cancer-associated fibroblasts.

Authors:  Haojun Luo; Guanglun Yang; Tenghua Yu; Shujuan Luo; Chengyi Wu; Yan Sun; Manran Liu; Gang Tu
Journal:  Endocr Relat Cancer       Date:  2014-03-07       Impact factor: 5.678
  9 in total

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