Literature DB >> 19444692

Calcitriol ointment: a review of a topical vitamin D analog for psoriasis.

Justin R Sigmon1, Brad A Yentzer, Steven R Feldman.   

Abstract

Topical vitamin D analogs are a safe and effective treatment for psoriasis vulgaris. This is a brief review of calcitriol 3 microg/g ointment in the treatment of psoriasis. Calcitriol has been safely used outside the USA in Europe under the trade name Silkis Ointment for almost a decade in the treatment of psoriasis, and it is currently FDA-approved as Vectical Ointment. Calcitriol 3 microg/g ointment is a synthetic topical vitamin D analog considered to be as effective as other vitamin D analogs but with a better tolerability in sensitive areas.

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Year:  2009        PMID: 19444692     DOI: 10.1080/09546630902936810

Source DB:  PubMed          Journal:  J Dermatolog Treat        ISSN: 0954-6634            Impact factor:   3.359


  5 in total

1.  Intradermal application of vitamin D3 increases migration of CD14+ dermal dendritic cells and promotes the development of Foxp3+ regulatory T cells.

Authors:  Ghaith Bakdash; Laura P Schneider; Toni M M van Capel; Martien L Kapsenberg; Marcel B M Teunissen; Esther C de Jong
Journal:  Hum Vaccin Immunother       Date:  2013-01-04       Impact factor: 3.452

2.  Topical 1,25-dihydroxyvitamin D3 subverts the priming ability of draining lymph node dendritic cells.

Authors:  Shelley Gorman; Melinda A Judge; Prue H Hart
Journal:  Immunology       Date:  2010-11       Impact factor: 7.397

3.  Identification of a Vitamin-D Receptor Antagonist, MeTC7, which Inhibits the Growth of Xenograft and Transgenic Tumors In Vivo.

Authors:  Negar Khazan; Kyu Kwang Kim; Jeanne N Hansen; Niloy A Singh; Taylor Moore; Cameron W A Snyder; Ravina Pandita; Myla Strawderman; Michiko Fujihara; Yuta Takamura; Ye Jian; Nicholas Battaglia; Naohiro Yano; Yuki Teramoto; Leggy A Arnold; Russell Hopson; Keshav Kishor; Sneha Nayak; Debasmita Ojha; Ashoke Sharon; John M Ashton; Jian Wang; Michael T Milano; Hiroshi Miyamoto; David C Linehan; Scott A Gerber; Nada Kawar; Ajay P Singh; Erdem D Tabdanov; Nikolay V Dokholyan; Hiroki Kakuta; Peter W Jurutka; Nina F Schor; Rachael B Rowswell-Turner; Rakesh K Singh; Richard G Moore
Journal:  J Med Chem       Date:  2022-04-11       Impact factor: 8.039

Review 4.  Calcitriol in Combination Therapy for Prostate Cancer: Pharmacokinetic and Pharmacodynamic Interactions.

Authors:  Mohamed Ben-Eltriki; Subrata Deb; Emma S Tomlinson Guns
Journal:  J Cancer       Date:  2016-01-15       Impact factor: 4.207

5.  Simulation of Physicochemical and Pharmacokinetic Properties of Vitamin D3 and Its Natural Derivatives.

Authors:  Subrata Deb; Anthony Allen Reeves; Suki Lafortune
Journal:  Pharmaceuticals (Basel)       Date:  2020-07-23
  5 in total

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