| Literature DB >> 19444143 |
Laima Siddiqi1, Jaap A Joles, Guido Grassi, Peter J Blankestijn.
Abstract
In chronic kidney disease simultaneous activation of the renin-angiotensin and sympathetic systems occurs. Kidney ischemia seems to play a key role in the pathogenesis. This review firstly summarizes experimental and clinical evidence in chronic kidney disease supporting this idea and addresses the possibility that this mechanism is also relevant in some other disease conditions.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19444143 DOI: 10.1097/HJH.0b013e32832b521b
Source DB: PubMed Journal: J Hypertens ISSN: 0263-6352 Impact factor: 4.844