BACKGROUND: Periodontal disease has been associated with increased perinatal mortality. AIMS: To examine the association between maternal periodontal disease and perinatal mortality. METHODS: We performed a retrospective and prospective matched case-control study of women with unexplained perinatal mortality at more than 20 weeks gestational age. Women were matched for socioeconomic status, smoking status and time since delivery. All women underwent a detailed periodontal examination and completed a questionnaire describing oral health symptoms. No intervention took place. RESULTS: Fifty-three women who had experienced a perinatal death and 111 controls completed the study. Thirty-two women were recruited retrospectively and 21 women were recruited prospectively. Twenty-three (43.4%) women who had experienced a perinatal death and 27 (24.3%) controls had periodontal disease. There were no differences in oral health behaviours or symptoms between cases and controls. Perinatal death was associated with periodontal disease (odds ratio (OR) 2.34, 95% confidence interval (CI) 1.05, 5.47). Periodontal disease was more strongly associated with perinatal mortality due to extreme prematurity (OR 3.60, 95% CI 1.20, 12.04). Multivariate analysis showed this relationship to be consistent after inclusion of higher parity, country of birth, advanced maternal age and maternal obesity in the model (OR 4.56, 95% CI 1.25, 21.27). CONCLUSIONS: Maternal periodontal disease may contribute to perinatal mortality, especially that caused by extreme prematurity.
BACKGROUND:Periodontal disease has been associated with increased perinatal mortality. AIMS: To examine the association between maternal periodontal disease and perinatal mortality. METHODS: We performed a retrospective and prospective matched case-control study of women with unexplained perinatal mortality at more than 20 weeks gestational age. Women were matched for socioeconomic status, smoking status and time since delivery. All women underwent a detailed periodontal examination and completed a questionnaire describing oral health symptoms. No intervention took place. RESULTS: Fifty-three women who had experienced a perinatal death and 111 controls completed the study. Thirty-two women were recruited retrospectively and 21 women were recruited prospectively. Twenty-three (43.4%) women who had experienced a perinatal death and 27 (24.3%) controls had periodontal disease. There were no differences in oral health behaviours or symptoms between cases and controls. Perinatal death was associated with periodontal disease (odds ratio (OR) 2.34, 95% confidence interval (CI) 1.05, 5.47). Periodontal disease was more strongly associated with perinatal mortality due to extreme prematurity (OR 3.60, 95% CI 1.20, 12.04). Multivariate analysis showed this relationship to be consistent after inclusion of higher parity, country of birth, advanced maternal age and maternal obesity in the model (OR 4.56, 95% CI 1.25, 21.27). CONCLUSIONS:Maternal periodontal disease may contribute to perinatal mortality, especially that caused by extreme prematurity.
Authors: Emily B Vander Schaaf; Rocio B Quinonez; Amanda C Cornett; Greg D Randolph; Kim Boggess; Kori B Flower Journal: Matern Child Health J Date: 2018-02
Authors: Bright Adu; Daniel Dodoo; Selorme Adukpo; Paula L Hedley; Fareed K N Arthur; Thomas A Gerds; Severin O Larsen; Michael Christiansen; Michael Theisen Journal: PLoS One Date: 2012-09-25 Impact factor: 3.240