Literature DB >> 19441129

Effect of cervical dystonia on employment: A retrospective analysis of the ability of treatment to restore premorbid employment status.

Eric S Molho1, Nitendra Agarwal, Katy Regan, Donald S Higgins, Stewart A Factor.   

Abstract

Using a structured interview method, we sought to address the following questions regarding cervical dystonia (CD) and employment: (1) what is the frequency and severity of job impairment in CD; (2) what are the clinical features that contribute to job impairment; (3) how does the effectiveness of botulinum toxin (BTx) compare to oral medications in restoring employment status. In our population of 155 CD patients, employment was affected by CD in 53.3% (31.2% reduced hours or responsibilities, 3.3% changed to different job, 18.9% loss of employment) and 68.9% of patients reported reduced overall productivity. The likelihood of altered employment (P < 0.0006), reduced productivity (P < 0.0001), and seeking disability benefits (P < 0.003) was significantly associated with the presence of neck pain, but not type of employment, spasmodic head motions, or duration of CD symptoms before treatment with BTx. Treatment with BTx was more likely to improve employment status than oral medications (66.1 vs. 18.5%) and much more likely to restore full employment with normal productivity (12.9 vs. 0.0%). These findings suggest that employment status is frequently affected by CD, particularly in patients withneck pain. BTx is significantly more effective than oral medications in restoring premorbid employment status. 2009 Movement Disorder Society.

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Year:  2009        PMID: 19441129     DOI: 10.1002/mds.22622

Source DB:  PubMed          Journal:  Mov Disord        ISSN: 0885-3185            Impact factor:   10.338


  15 in total

Review 1.  Dystonia: phenomenology.

Authors:  Mark S LeDoux
Journal:  Parkinsonism Relat Disord       Date:  2012-01       Impact factor: 4.891

Review 2.  The effectiveness of physiotherapy for cervical dystonia: a systematic literature review.

Authors:  Joke De Pauw; Kevin Van der Velden; Jill Meirte; Ulrike Van Daele; Steven Truijen; Patrick Cras; Rudy Mercelis; Willem De Hertogh
Journal:  J Neurol       Date:  2014-01-12       Impact factor: 4.849

3.  Head tremor and pain in cervical dystonia.

Authors:  Jeanne P Vu; Ha Yeon Lee; Qiyu Chen; Elizabeth Cisneros; Richard L Barbano; Christopher G Goetz; Joseph Jankovic; Hyder A Jinnah; Joel S Perlmutter; Brian D Berman; Mark I Appelbaum; Glenn T Stebbins; Cynthia L Comella; David A Peterson
Journal:  J Neurol       Date:  2021-01-08       Impact factor: 4.849

Review 4.  Botulinum toxin as treatment for focal dystonia: a systematic review of the pharmaco-therapeutic and pharmaco-economic value.

Authors:  E Zoons; M G W Dijkgraaf; J M Dijk; I N van Schaik; M A Tijssen
Journal:  J Neurol       Date:  2012-05-03       Impact factor: 4.849

5.  Rationale and design of a prospective study: Cervical Dystonia Patient Registry for Observation of OnaBotulinumtoxinA Efficacy (CD PROBE).

Authors:  Joseph Jankovic; Charles H Adler; P David Charles; Cynthia Comella; Mark Stacy; Marc Schwartz; Susan M Sutch; Mitchell F Brin; Spyridon Papapetropoulos
Journal:  BMC Neurol       Date:  2011-11-04       Impact factor: 2.474

6.  Head tremor in cervical dystonia: Quantifying severity with computer vision.

Authors:  Jeanne P Vu; Elizabeth Cisneros; Ha Yeon Lee; Linh Le; Qiyu Chen; Xiaoyan A Guo; Ryin Rouzbehani; Joseph Jankovic; Stewart Factor; Christopher G Goetz; Richard L Barbano; Joel S Perlmutter; Hyder A Jinnah; Sarah Pirio Richardson; Glenn T Stebbins; Rodger Elble; Cynthia L Comella; David A Peterson
Journal:  J Neurol Sci       Date:  2022-01-22       Impact factor: 4.553

7.  AbobotulinumtoxinA in the management of cervical dystonia in the United Kingdom: a budget impact analysis.

Authors:  Seye Abogunrin; Sarah Brand; Kamal Desai; Jerome Dinet; Sylvie Gabriel; Timothy Harrower
Journal:  Clinicoecon Outcomes Res       Date:  2015-09-09

8.  Exploring factors related to physical activity in cervical dystonia.

Authors:  Lena Zetterberg; Charlotte Urell; Elisabeth Anens
Journal:  BMC Neurol       Date:  2015-12-01       Impact factor: 2.474

9.  Prospective Study Evaluating IncobotulinumtoxinA for Cervical Dystonia or Blepharospasm: Interim Results from the First 145 Subjects with Cervical Dystonia.

Authors:  Hubert H Fernandez; Fernando Pagan; Fabio Danisi; David Greeley; Joseph Jankovic; Amit Verma; Kapil Sethi; Eric J Pappert
Journal:  Tremor Other Hyperkinet Mov (N Y)       Date:  2013-05-17

10.  An open-label cohort study of the improvement of quality of life and pain in de novo cervical dystonia patients after injections with 500 U botulinum toxin A (Dysport).

Authors:  H Hefter; R Benecke; F Erbguth; W Jost; G Reichel; J Wissel
Journal:  BMJ Open       Date:  2013-04-18       Impact factor: 2.692

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