BACKGROUND: Bone substitutes, such as allografts, xenografts, and alloplasts, have been proposed in several augmentation procedures. PURPOSE: The aim of the present study was a histologic and histomorphometric evaluation of specimens retrieved 4 or 6 months after sinus augmentation using cortical porcine bone augmentation material. MATERIALS AND METHODS: A total of 77 specimens, retrieved after 4 and 6 months from augmented sinuses, were used in this study. The specimens were processed to be observed under light microscopy. Histomorphometric measurements were presented as means ± standard deviations. RESULTS: Most of the particles were surrounded by newly formed bone with large osteocyte lacunae. Histomorphometry showed that, after 4 months, the newly formed bone represented 28%, marrow spaces 36%, the residual graft material 37%, while, after 6 months, the newly formed bone represented 31%, marrow spaces 34%, while the residual graft material was 37%. CONCLUSION: The present results show that cortical porcine bone is a biocompatible, osteoconductive biomaterial that can be used for maxillary sinus augmentation procedures without interfering with the normal reparative bone processes.
BACKGROUND: Bone substitutes, such as allografts, xenografts, and alloplasts, have been proposed in several augmentation procedures. PURPOSE: The aim of the present study was a histologic and histomorphometric evaluation of specimens retrieved 4 or 6 months after sinus augmentation using cortical porcine bone augmentation material. MATERIALS AND METHODS: A total of 77 specimens, retrieved after 4 and 6 months from augmented sinuses, were used in this study. The specimens were processed to be observed under light microscopy. Histomorphometric measurements were presented as means ± standard deviations. RESULTS: Most of the particles were surrounded by newly formed bone with large osteocyte lacunae. Histomorphometry showed that, after 4 months, the newly formed bone represented 28%, marrow spaces 36%, the residual graft material 37%, while, after 6 months, the newly formed bone represented 31%, marrow spaces 34%, while the residual graft material was 37%. CONCLUSION: The present results show that cortical porcine bone is a biocompatible, osteoconductive biomaterial that can be used for maxillary sinus augmentation procedures without interfering with the normal reparative bone processes.
Authors: Antonio Scarano; Felice Lorusso; Lorenzo Ravera; Carmen Mortellaro; Adriano Piattelli Journal: Biomed Res Int Date: 2016-05-30 Impact factor: 3.411
Authors: María Piedad Ramírez Fernández; Patricia Mazón; Sergio A Gehrke; Jose Luis Calvo-Guirado; Piedad N De Aza Journal: Materials (Basel) Date: 2017-06-07 Impact factor: 3.623
Authors: Carlo Mangano; Alessandra Giuliani; Ilaria De Tullio; Mario Raspanti; Adriano Piattelli; Giovanna Iezzi Journal: Front Bioeng Biotechnol Date: 2021-04-15