Migraine following trans-septal access for catheter ablation of cardiac arrhythmias.

There is increasing recognition that migraine with aura may be associated with intra-cardiac shunting because of a patent foramen ovale. Radio-frequency ablation to treat cardiac arrhythmias is an increasingly popular means of treating cardiac arrhythmias. Trans-septal puncture is routinely performed to gain access to the left atrium in order to ablate arrhythmias originating in the left heart. We report several cases of migraine triggered acutely by trans-septal puncture at our center.