Literature DB >> 19438562

Silicone breast implant rupture presenting as bilateral leg nodules.

L Sagi1, S Baum, A Lyakhovitsky, A Barzilai, D Shpiro, H Trau, O Goldan, E Winkler.   

Abstract

Gross migration of silicone gel from ruptured breast implants is a rare event. It is associated with extravasation of gel into the breast parenchyma, and to distant locations such as the abdominal wall and inguinal areas. This silicone deposits present as subcutaneous nodules and cause a local reaction known as siliconoma. We evaluated a 56-year-old woman who presented with a 2-year history of painful, firm and ill-defined subcutaneous nodules on the medial aspect of the shins and ankles. Her medical history was notable for bilateral breast augmentation with silicone implants 30 years before presentation. Although there were no signs or symptoms on breast examination, ultrasonography and magnetic resonance imaging confirmed that both implants had ruptured. Histological examination of a punch biopsy from a nodule on the shin found lobular granulomatous panniculitis. An excisional biopsy of the lesion was analysed by scanning electron microscopy and was found to contain silicone. This is a rare case of gross migration of silicone to the shins, originating from ruptured breast implants. To our knowledge, there is no previous report of silicone migration to such a distant location. We discuss the common presentation of silicone migration and highlight the importance of awareness among dermatologists and plastic surgeons about this unusual occurrence.

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Year:  2009        PMID: 19438562     DOI: 10.1111/j.1365-2230.2008.03196.x

Source DB:  PubMed          Journal:  Clin Exp Dermatol        ISSN: 0307-6938            Impact factor:   3.470


  7 in total

Review 1.  Autoimmune/inflammatory syndrome induced by adjuvants (ASIA): clues and pitfalls in the pediatric background.

Authors:  Susanna Esposito; Elisabetta Prada; Maria Vincenza Mastrolia; Giusyda Tarantino; Claudio Codecà; Donato Rigante
Journal:  Immunol Res       Date:  2014-12       Impact factor: 2.829

Review 2.  ASIA syndrome, calcinosis cutis and chronic kidney disease following silicone injections. A case-based review.

Authors:  Giuseppe Barilaro; Claudia Spaziani Testa; Antonella Cacciani; Giuseppe Donato; Mira Dimko; Amalia Mariotti
Journal:  Immunol Res       Date:  2016-12       Impact factor: 2.829

3.  Radiological pitfall: Siliconoma in internal mammary lymph node mimics breast cancer recurrence.

Authors:  Karen Steinke; Phillipa Brook; Olivier Ramuz
Journal:  Radiol Case Rep       Date:  2015-11-06

4.  Distant Migration of Multiple Siliconomas in Lower Extremities following Breast Implant Rupture: Case Report.

Authors:  Joo Hyun Oh; Seung Yong Song; Dae Hyun Lew; Dong Won Lee
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-10-27

5.  Safety of Copolyamide Filler Injection for Breast Augmentation.

Authors:  Shunichi Nomoto; Keiko Hirakawa; Rei Ogawa
Journal:  Plast Reconstr Surg Glob Open       Date:  2021-02-17

6.  Video Q&A: what is ASIA? An interview with Yehuda Shoenfeld.

Authors:  Yehuda Shoenfeld
Journal:  BMC Med       Date:  2013-05-01       Impact factor: 8.775

7.  Silicone Migration and Late Hematoma following Silicone Implant Rupture: Case Report and Literature Review.

Authors:  Riley A Dean; Adam D Glener; Analise B Thomas; Steven R Glener; Silvia Kurtovic; Detlev Erdmann
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-08-06
  7 in total

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