Literature DB >> 19437525

Selective antifolates for chemically labeling proteins in mammalian cells.

Laura E Pedró Rosa1, D Rajasekhar Reddy, Sherry F Queener, Lawrence W Miller.   

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Year:  2009        PMID： 19437525      PMCID： PMC3415248          DOI： 10.1002/cbic.200900152

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  19 in total

Review 1.  Unnatural ligands for engineered proteins: new tools for chemical genetics.

Authors:  A Bishop; O Buzko; S Heyeck-Dumas; I Jung; B Kraybill; Y Liu; K Shah; S Ulrich; L Witucki; F Yang; C Zhang; K M Shokat
Journal:  Annu Rev Biophys Biomol Struct       Date:  2000

2.  Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three major opportunistic pathogens of AIDS.

Authors:  Andre Rosowsky; Ronald A Forsch; Sherry F Queener
Journal:  J Med Chem       Date:  2003-04-24       Impact factor: 7.446

3.  An orthogonal dexamethasone-trimethoprim yeast three-hybrid system.

Authors:  Sarah S Gallagher; Lawrence W Miller; Virginia W Cornish
Journal:  Anal Biochem       Date:  2006-12-28       Impact factor: 3.365

4.  Inhibition of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductases by 2,4-diamino-5-[2-methoxy-5-(omega-carboxyalkyloxy)benzyl]pyrimidines: marked improvement in potency relative to trimethoprim and species selectivity relative to piritrexim.

Authors:  Andre Rosowsky; Ronald A Forsch; Sherry F Queener
Journal:  J Med Chem       Date:  2002-01-03       Impact factor: 7.446

5.  New insights into DHFR interactions: analysis of Pneumocystis carinii and mouse DHFR complexes with NADPH and two highly potent 5-(omega-carboxy(alkyloxy) trimethoprim derivatives reveals conformational correlations with activity and novel parallel ring stacking interactions.

Authors:  Vivian Cody; Jim Pace; Kim Chisum; Andre Rosowsky
Journal:  Proteins       Date:  2006-12-01

6.  Development of 2,4-diaminopyrimidines as antimalarials based on inhibition of the S108N and C59R+S108N mutants of dihydrofolate reductase from pyrimethamine-resistant Plasmodium falciparum.

Authors:  Bongkoch Tarnchompoo; Chawanee Sirichaiwat; Worrapong Phupong; Chakapong Intaraudom; Worachart Sirawaraporn; Sumalee Kamchonwongpaisan; Jarunee Vanichtanankul; Yodhathai Thebtaranonth; Yongyuth Yuthavong
Journal:  J Med Chem       Date:  2002-03-14       Impact factor: 7.446

7.  Structure-based design of selective inhibitors of dihydrofolate reductase: synthesis and antiparasitic activity of 2, 4-diaminopteridine analogues with a bridged diarylamine side chain.

Authors:  A Rosowsky; V Cody; N Galitsky; H Fu; A T Papoulis; S F Queener
Journal:  J Med Chem       Date:  1999-11-18       Impact factor: 7.446

8.  Optimized fluorescent trimethoprim derivatives for in vivo protein labeling.

Authors:  Nathaniel T Calloway; Michael Choob; Ana Sanz; Michael P Sheetz; Lawrence W Miller; Virginia W Cornish
Journal:  Chembiochem       Date:  2007-05-07       Impact factor: 3.164

9.  Target guided synthesis of 5-benzyl-2,4-diamonopyrimidines: their antimalarial activities and binding affinities to wild type and mutant dihydrofolate reductases from Plasmodium falciparum.

Authors:  Chawanee Sirichaiwat; Chakapong Intaraudom; Sumalee Kamchonwongpaisan; Jarunee Vanichtanankul; Yodhathai Thebtaranonth; Yongyuth Yuthavong
Journal:  J Med Chem       Date:  2004-01-15       Impact factor: 7.446

10.  Conditional glycosylation in eukaryotic cells using a biocompatible chemical inducer of dimerization.

Authors:  Jennifer L Czlapinski; Michael W Schelle; Lawrence W Miller; Scott T Laughlin; Jennifer J Kohler; Virginia W Cornish; Carolyn R Bertozzi
Journal:  J Am Chem Soc       Date:  2008-09-13       Impact factor: 15.419
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