Literature DB >> 19436918

A chemoenzymatic route to N-acetylglucosamine-1-phosphate analogues: substrate specificity investigations of N-acetylhexosamine 1-kinase.

Li Cai1, Wanyi Guan, Motomitsu Kitaoka, Jie Shen, Chengfeng Xia, Wenlan Chen, Peng George Wang.   

Abstract

Reports an efficient chemoenzymatic production of an N-acetylhexosamine 1-phophate analogues library by N-acetylhexosamine 1-kinase (NahK) and describes the respective substrate specificity on this enzyme.

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Year:  2009        PMID： 19436918     DOI： 10.1039/b904853g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  19 in total

1.  Highly efficient synthesis of UDP-GalNAc/GlcNAc analogues with promiscuous recombinant human UDP-GalNAc pyrophosphorylase AGX1.

Authors:  Wanyi Guan; Li Cai; Peng George Wang
Journal:  Chemistry       Date:  2010-12-03       Impact factor: 5.236

2.  Comparing substrate specificity of two UDP-sugar pyrophosphorylases and efficient one-pot enzymatic synthesis of UDP-GlcA and UDP-GalA.

Authors:  Yuxi Guo; Junqiang Fang; Tiehai Li; Xu Li; Cheng Ma; Xuan Wang; Peng G Wang; Lei Li
Journal:  Carbohydr Res       Date:  2015-04-16       Impact factor: 2.104

3.  Efficient enzymatic synthesis of guanosine 5'-diphosphate-sugars and derivatives.

Authors:  Lei Li; Yonghui Liu; Yue Wan; Yanhong Li; Xi Chen; Wei Zhao; Peng George Wang
Journal:  Org Lett       Date:  2013-10-11       Impact factor: 6.005

4.  Exploiting metabolic glycoengineering to advance healthcare.

Authors:  Christian Agatemor; Matthew J Buettner; Ryan Ariss; Keerthana Muthiah; Christopher T Saeui; Kevin J Yarema
Journal:  Nat Rev Chem       Date:  2019-09-06       Impact factor: 34.035

5.  Chemoenzymatic synthesis of uridine 5'-diphospho-2-acetonyl-2-deoxy-alpha-D-glucose as C(2)-carbon isostere of UDP-GlcNAc.

Authors:  Li Cai; Wanyi Guan; Wenlan Chen; Peng George Wang
Journal:  J Org Chem       Date:  2010-05-21       Impact factor: 4.354

6.  Chemoenzymatic synthesis of ADP-d-glycero-β-d-manno-heptose and study of the substrate specificity of HldE.

Authors:  Tiehai Li; Liuqing Wen; Adriel Williams; Baolin Wu; Lei Li; Jingyao Qu; Jeffrey Meisner; Zhongying Xiao; Junqiang Fang; Peng George Wang
Journal:  Bioorg Med Chem       Date:  2013-12-19       Impact factor: 3.641

7.  Facile chemoenzymatic synthesis of biotinylated heparosan hexasaccharide.

Authors:  Baolin Wu; Na Wei; Vireak Thon; Mohui Wei; Zaikuan Yu; Yongmei Xu; Xi Chen; Jian Liu; Peng George Wang; Tiehai Li
Journal:  Org Biomol Chem       Date:  2015-05-14       Impact factor: 3.876

8.  Enzymatic synthesis and properties of uridine-5'-O-(2-thiodiphospho)-N-acetylglucosamine.

Authors:  Li Cai; Lan Ban; Wanyi Guan; Milan Mrksich; Peng George Wang
Journal:  Carbohydr Res       Date:  2011-05-12       Impact factor: 2.104

9.  Phosphoryl transfer from α-d-glucose 1-phosphate catalyzed by Escherichia coli sugar-phosphate phosphatases of two protein superfamily types.

Authors:  Patricia Wildberger; Martin Pfeiffer; Lothar Brecker; Gerald N Rechberger; Ruth Birner-Gruenberger; Bernd Nidetzky
Journal:  Appl Environ Microbiol       Date:  2014-12-19       Impact factor: 4.792

10.  Enzymatic route to preparative-scale synthesis of UDP-GlcNAc/GalNAc, their analogues and GDP-fucose.

Authors:  Guohui Zhao; Wanyi Guan; Li Cai; Peng George Wang
Journal:  Nat Protoc       Date:  2010-03-11       Impact factor: 13.491
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