Literature DB >> 19436897

New method to prepare very stable and biocompatible fluorescent silica nanoparticles.

Shin-Woo Ha1, Corinne E Camalier, George R Beck, Jin-Kyu Lee.   

Abstract

A new synthetic method has been developed to prepare fluorescent silica nanoparticles without employing isothiocyanated dye molecules and (3-aminopropyl)triethoxysilane (APS) for the thiourea linkage formation; the resulting fluorescent silica nanoparticles show excellent photochemical, thermal and pH stabilities and a good biocompatibility with over 85% viability from various cell types.

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Year:  2009        PMID： 19436897      PMCID： PMC2879016          DOI： 10.1039/b902195g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  16 in total

1.  In vitro toxicity of silica nanoparticles in human lung cancer cells.

Authors:  Weisheng Lin; Yue-Wern Huang; Xiao-Dong Zhou; Yinfa Ma
Journal:  Toxicol Appl Pharmacol       Date:  2006-10-06       Impact factor: 4.219

2.  Multifunctional nanoparticles possessing a "magnetic motor effect" for drug or gene delivery.

Authors:  Tae-Jong Yoon; Jun Sung Kim; Byung Geol Kim; Kyeong Nam Yu; Myung-Haing Cho; Jin-Kyu Lee
Journal:  Angew Chem Int Ed Engl       Date:  2005-02-04       Impact factor: 15.336

3.  Optical tracking of organically modified silica nanoparticles as DNA carriers: a nonviral, nanomedicine approach for gene delivery.

Authors:  Indrajit Roy; Tymish Y Ohulchanskyy; Dhruba J Bharali; Haridas E Pudavar; Ruth A Mistretta; Navjot Kaur; Paras N Prasad
Journal:  Proc Natl Acad Sci U S A       Date:  2005-01-03       Impact factor: 11.205

Review 4.  Intracellular trafficking pathways and drug delivery: fluorescence imaging of living and fixed cells.

Authors:  Peter Watson; Arwyn T Jones; David J Stephens
Journal:  Adv Drug Deliv Rev       Date:  2005-01-02       Impact factor: 15.470

5.  Cellular fate of a modular DNA delivery system mediated by silica nanoparticles.

Authors:  Richard A Gemeinhart; Dan Luo; W Mark Saltzman
Journal:  Biotechnol Prog       Date:  2005 Mar-Apr

6.  Bright and stable core-shell fluorescent silica nanoparticles.

Authors:  Hooisweng Ow; Daniel R Larson; Mamta Srivastava; Barbara A Baird; Watt W Webb; Ulrich Wiesner
Journal:  Nano Lett       Date:  2005-01       Impact factor: 11.189

7.  Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers.

Authors:  S Santra; P Zhang; K Wang; R Tapec; W Tan
Journal:  Anal Chem       Date:  2001-10-15       Impact factor: 6.986

8.  Formation of nucleoplasmic protein aggregates impairs nuclear function in response to SiO2 nanoparticles.

Authors:  Min Chen; Anna von Mikecz
Journal:  Exp Cell Res       Date:  2005-01-24       Impact factor: 3.905

9.  Toxicity and tissue distribution of magnetic nanoparticles in mice.

Authors:  Jun Sung Kim; Tae-Jong Yoon; Kyeong Nam Yu; Byung Gul Kim; Sung Jin Park; Hyun Woo Kim; Kee Ho Lee; Seung Bum Park; Jin-Kyu Lee; Myung Haing Cho
Journal:  Toxicol Sci       Date:  2005-10-19       Impact factor: 4.849

10.  Cellular uptake and cytotoxicity of silica nanotubes.

Authors:  Anjan Nan; Xia Bai; Sang Jun Son; Sang Bok Lee; Hamidreza Ghandehari
Journal:  Nano Lett       Date:  2008-07-12       Impact factor: 11.189
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  16 in total

1.  Bio-active engineered 50 nm silica nanoparticles with bone anabolic activity: therapeutic index, effective concentration, and cytotoxicity profile in vitro.

Authors:  Shin-Woo Ha; James A Sikorski; M Neale Weitzmann; George R Beck
Journal:  Toxicol In Vitro       Date:  2013-12-12       Impact factor: 3.500

2.  LONG-TERM MONITORING OF THE PHYSICOCHEMICAL PROPERTIES OF SILICA-BASED NANOPARTICLES ON THE RATE OF ENDOCYTOSIS AND EXOCYTOSIS AND CONSEQUENCES OF CELL DIVISION.

Authors:  Shin-Woo Ha; Corinne E Camalier; M Neale Weitzmann; George R Beck; Jin-Kyu Lee
Journal:  Soft Mater       Date:  2013-04-01       Impact factor: 2.429

3.  Nano-hydroxyapatite modulates osteoblast lineage commitment by stimulation of DNA methylation and regulation of gene expression.

Authors:  Shin-Woo Ha; Hae Lin Jang; Ki Tae Nam; George R Beck
Journal:  Biomaterials       Date:  2015-06-23       Impact factor: 12.479

4.  Bioactive silica-based nanoparticles stimulate bone-forming osteoblasts, suppress bone-resorbing osteoclasts, and enhance bone mineral density in vivo.

Authors:  George R Beck; Shin-Woo Ha; Corinne E Camalier; Masayoshi Yamaguchi; Yan Li; Jin-Kyu Lee; M Neale Weitzmann
Journal:  Nanomedicine       Date:  2011-11-16       Impact factor: 5.307

5.  Synthesis and biological response of size-specific, monodisperse drug-silica nanoconjugates.

Authors:  Li Tang; Timothy M Fan; Luke B Borst; Jianjun Cheng
Journal:  ACS Nano       Date:  2012-04-24       Impact factor: 15.881

6.  Size-dependent tumor penetration and in vivo efficacy of monodisperse drug-silica nanoconjugates.

Authors:  Li Tang; Nathan P Gabrielson; Fatih M Uckun; Timothy M Fan; Jianjun Cheng
Journal:  Mol Pharm       Date:  2013-02-12       Impact factor: 4.939

7.  Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugates for targeted dual-modal imaging of lymph nodes with metastatic tumors.

Authors:  Li Tang; Xujuan Yang; Lawrence W Dobrucki; Isthier Chaudhury; Qian Yin; Catherine Yao; Stéphane Lezmi; William G Helferich; Timothy M Fan; Jianjun Cheng
Journal:  Angew Chem Int Ed Engl       Date:  2012-11-07       Impact factor: 15.336

8.  A comparative study of non-covalent encapsulation methods for organic dyes into silica nanoparticles.

Authors:  Aurélien Auger; Jorice Samuel; Olivier Poncelet; Olivier Raccurt
Journal:  Nanoscale Res Lett       Date:  2011-04-13       Impact factor: 4.703

9.  Bioactive silica nanoparticles reverse age-associated bone loss in mice.

Authors:  M Neale Weitzmann; Shin-Woo Ha; Tatyana Vikulina; Susanne Roser-Page; Jin-Kyu Lee; George R Beck
Journal:  Nanomedicine       Date:  2015-02-11       Impact factor: 5.307

10.  Bioactive silica nanoparticles promote osteoblast differentiation through stimulation of autophagy and direct association with LC3 and p62.

Authors:  Shin-Woo Ha; M Neale Weitzmann; George R Beck
Journal:  ACS Nano       Date:  2014-05-14       Impact factor: 15.881
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