Literature DB >> 19435982

Toxicity testing in the 21st century: a view from the pharmaceutical industry.

James S MacDonald1, Richard T Robertson.   

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Year:  2009        PMID： 19435982     DOI： 10.1093/toxsci/kfp088

Source DB:  PubMed          Journal:  Toxicol Sci        ISSN： 1096-0929            Impact factor:   4.849


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  21 in total

1.  Identification and characterization of adverse effects in 21st century toxicology.

Authors:  Douglas A Keller; Daland R Juberg; Natasha Catlin; William H Farland; Frederick G Hess; Douglas C Wolf; Nancy G Doerrer
Journal:  Toxicol Sci       Date:  2012-01-19       Impact factor: 4.849

2.  FutureTox II: in vitro data and in silico models for predictive toxicology.

Authors:  Thomas B Knudsen; Douglas A Keller; Miriam Sander; Edward W Carney; Nancy G Doerrer; David L Eaton; Suzanne Compton Fitzpatrick; Kenneth L Hastings; Donna L Mendrick; Raymond R Tice; Paul B Watkins; Maurice Whelan
Journal:  Toxicol Sci       Date:  2015-02       Impact factor: 4.849

Review 3.  The Impact of Novel Assessment Methodologies in Toxicology on Green Chemistry and Chemical Alternatives.

Authors:  Ivan Rusyn; Nigel Greene
Journal:  Toxicol Sci       Date:  2018-02-01       Impact factor: 4.849

Review 4.  Cryopreservation of Human Pluripotent Stem Cell-Derived Cardiomyocytes: Strategies, Challenges, and Future Directions.

Authors:  Marcela K Preininger; Monalisa Singh; Chunhui Xu
Journal:  Adv Exp Med Biol       Date:  2016       Impact factor: 2.622

5.  Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins.

Authors:  H H J Gerets; K Tilmant; B Gerin; H Chanteux; B O Depelchin; S Dhalluin; F A Atienzar
Journal:  Cell Biol Toxicol       Date:  2012-01-19       Impact factor: 6.691

Review 6.  Mechanistic biomarkers in acetaminophen-induced hepatotoxicity and acute liver failure: from preclinical models to patients.

Authors:  Mitchell R McGill; Hartmut Jaeschke
Journal:  Expert Opin Drug Metab Toxicol       Date:  2014-05-16       Impact factor: 4.481

Review 7.  Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways.

Authors:  Sudin Bhattacharya; Qiang Zhang; Paul L Carmichael; Kim Boekelheide; Melvin E Andersen
Journal:  PLoS One       Date:  2011-06-20       Impact factor: 3.240

Review 8.  The case for induced pluripotent stem cell-derived cardiomyocytes in pharmacological screening.

Authors:  Jaffar M Khan; Alexander R Lyon; Sian E Harding
Journal:  Br J Pharmacol       Date:  2013-05       Impact factor: 8.739

9.  Cardiac Safety of Kinase Inhibitors - Improving Understanding and Prediction of Liabilities in Drug Discovery Using Human Stem Cell-Derived Models.

Authors:  Ricarda Ziegler; Fabian Häusermann; Stephan Kirchner; Liudmila Polonchuk
Journal:  Front Cardiovasc Med       Date:  2021-06-16

10.  Comparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict a risk of drug induced hepatotoxicity.

Authors:  Monika Szabo; Zsuzsa Veres; Zsolt Baranyai; Ferenc Jakab; Katalin Jemnitz
Journal:  PLoS One       Date:  2013-03-14       Impact factor: 3.240
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