INTRODUCTION: There is a lack of data about post-traumatic stress disorder (PTSD) in European bipolar patients compared to the US-population. This study was conducted to ascertain the rates and types of traumatic events and PTSD in bipolar-I disorder. METHODS: Euthymic bipolar patients were screened for lifetime diagnosis of PTSD using the Post-Traumatic Stress Diagnostic Scale and the Clinician Administered Post-traumatic Stress Disorder Scale. RESULTS: A total of 74 patients (m = 30, f = 44) with diagnosis of bipolar-I disorder were assessed. 37 patients (50%) reported no trauma, 22 patients (29.7%) experienced traumatic events without diagnosis of PTSD and 15 patients (20.3%) had comorbid PTSD. Bipolar PTSD patients were at higher risk to be exposed to physical violence, parental disregard, alcohol dependence of parents, sexual assault by a family member or acquaintance. The number of siblings was higher and they had higher scores on the Hamilton Depression Rating Scale and the Global Assessment of Functioning Scale. CONCLUSIONS: Bipolar patients are more likely to experience traumatic events and PTSD is a relevant comorbid disorder. PTSD is associated with an increased illness severity of bipolar disorder.
INTRODUCTION: There is a lack of data about post-traumatic stress disorder (PTSD) in European bipolarpatients compared to the US-population. This study was conducted to ascertain the rates and types of traumatic events and PTSD in bipolar-I disorder. METHODS: Euthymic bipolarpatients were screened for lifetime diagnosis of PTSD using the Post-Traumatic Stress Diagnostic Scale and the Clinician Administered Post-traumatic Stress Disorder Scale. RESULTS: A total of 74 patients (m = 30, f = 44) with diagnosis of bipolar-I disorder were assessed. 37 patients (50%) reported no trauma, 22 patients (29.7%) experienced traumatic events without diagnosis of PTSD and 15 patients (20.3%) had comorbid PTSD. BipolarPTSDpatients were at higher risk to be exposed to physical violence, parental disregard, alcohol dependence of parents, sexual assault by a family member or acquaintance. The number of siblings was higher and they had higher scores on the Hamilton Depression Rating Scale and the Global Assessment of Functioning Scale. CONCLUSIONS:Bipolarpatients are more likely to experience traumatic events and PTSD is a relevant comorbid disorder. PTSD is associated with an increased illness severity of bipolar disorder.
Authors: Mark H Pollack; Naomi M Simon; Andrea Fagiolini; Roger Pitman; Richard J McNally; Andrew A Nierenberg; Sachicko Miyahara; Gary S Sachs; Carol Perlman; S Nassir Ghaemi; Michael E Thase; Michael W Otto Journal: J Clin Psychiatry Date: 2006-03 Impact factor: 4.384
Authors: D V Sheehan; Y Lecrubier; K H Sheehan; P Amorim; J Janavs; E Weiller; T Hergueta; R Baker; G C Dunbar Journal: J Clin Psychiatry Date: 1998 Impact factor: 4.384
Authors: Claudia Carmassi; Paolo Stratta; Gabriele Massimetti; Carlo Antonio Bertelloni; Ciro Conversano; Ivan Mirko Cremone; Mario Miccoli; Angelo Baggiani; Alessandro Rossi; Liliana Dell'Osso Journal: Ann Gen Psychiatry Date: 2014-11-18 Impact factor: 3.455