Miguel A Vazquez1. 1. University of Texas Southwestern Medical Center, Dallas, Texas 75390-8856, USA. miguel.vazquez@utsouthwestern.edu
Abstract
PURPOSE OF REVIEW: Vascular access complications are a major cause of excessive morbidity and mortality in the dialysis population. This review will focus on recent changes in vascular access practices and access management directly affecting patient outcomes. RECENT FINDINGS: The proportion of patients dialyzing via arteriovenous fistulas continues to increase as a result of national initiatives. Maturation failure is now the main obstacle to successful use of fistulas. Arteriovenous grafts remain an important vascular access option for dialysis, and interventions to prevent progression of stenosis are being explored. Central venous catheter prevalence has increased and new interventions to address catheter-related complications such as thrombosis and infection are promising. SUMMARY: Advances in understanding the factors related to fistula maturation failure will have a major beneficial effect on vascular access outcomes. New approaches to prevent graft and catheter-related complications should complement advances on fistula management. Optimal patient selection for specific access modalities and institution of timely access interventions tested in rigorous clinical trials should be the next step to improve access management.
PURPOSE OF REVIEW: Vascular access complications are a major cause of excessive morbidity and mortality in the dialysis population. This review will focus on recent changes in vascular access practices and access management directly affecting patient outcomes. RECENT FINDINGS: The proportion of patients dialyzing via arteriovenous fistulas continues to increase as a result of national initiatives. Maturation failure is now the main obstacle to successful use of fistulas. Arteriovenous grafts remain an important vascular access option for dialysis, and interventions to prevent progression of stenosis are being explored. Central venous catheter prevalence has increased and new interventions to address catheter-related complications such as thrombosis and infection are promising. SUMMARY: Advances in understanding the factors related to fistula maturation failure will have a major beneficial effect on vascular access outcomes. New approaches to prevent graft and catheter-related complications should complement advances on fistula management. Optimal patient selection for specific access modalities and institution of timely access interventions tested in rigorous clinical trials should be the next step to improve access management.
Authors: Ioannis Kourtzelis; Maciej M Markiewski; Michael Doumas; Stavros Rafail; Konstantinos Kambas; Ioannis Mitroulis; Stelios Panagoutsos; Ploumis Passadakis; Vasilios Vargemezis; Paola Magotti; Hongchang Qu; Tom Eirik Mollnes; Konstantinos Ritis; John D Lambris Journal: Blood Date: 2010-04-27 Impact factor: 22.113
Authors: Daniel Y Lu; Elizabeth Y Chen; Daniel J Wong; Kota Yamamoto; Clinton D Protack; Willis T Williams; Roland Assi; Michael R Hall; Nirvana Sadaghianloo; Alan Dardik Journal: J Surg Res Date: 2014-01-30 Impact factor: 2.192