| Literature DB >> 19433911 |
L-P Zhang1, Q-F Gan, X-H Zhang, H-D Li, G-Y Hou, J-Y Li, X Gao, H-Y Ren, J-B Chen, S-Z Xu.
Abstract
The aim of this study was to detect polymorphism in the bovine bone morphogenetic protein 15 (BMP15) gene. On the basis of PCR-SSCP and DNA sequencing, a 4-bp deletion was identified in the coding region of the gene. Sequence analysis revealed that the deletion altered the reading frame and introduced a stop codon at position 264. Eight breeds (Luxi, Qinchuan, Nanyang, Jinnan, Bohai Black, Menggolian, Holstein, and Simmental) were genotyped by PCR-SSCP. No cows homozygous for this mutation were observed in these breeds. Heterozygous cows were detected in Luxi, Qinchuan, Nanyang, Jinnan and Bohai Black cattle. Fecundity was not increased in heterozygous individuals.Entities:
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Year: 2009 PMID： 19433911 DOI： 10.1007/BF03195665
Source DB: PubMed Journal: J Appl Genet ISSN： 1234-1983 Impact factor: 3.240