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Literature DB >> 19433600

Decreased Paneth cell defensin expression in ileal Crohn's disease is independent of inflammation, but linked to the NOD2 1007fs genotype.

C L Bevins, E F Stange, J Wehkamp.

Abstract

Entities: Disease Gene

Mesh：

Substances：

Year: 2009 PMID： 19433600

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

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29 in total

1. Linkage between genotype and immunological phenotype in Crohn's disease.

Authors: Gwenny M Fuhler; Kaushal Parikh; C Janneke van der Woude; Maikel P Peppelenbosch
Journal: Ann Transl Med Date: 2015-09

2. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.

Authors: Simon A Hirota; Jeffrey Ng; Alan Lueng; Maitham Khajah; Ken Parhar; Yan Li; Victor Lam; Mireille S Potentier; Kelvin Ng; Misha Bawa; Donna-Marie McCafferty; Kevin P Rioux; Subrata Ghosh; Ramnik J Xavier; Sean P Colgan; Jurg Tschopp; Daniel Muruve; Justin A MacDonald; Paul L Beck
Journal: Inflamm Bowel Dis Date: 2010-09-24 Impact factor: 5.325

Review 3. Defensins couple dysbiosis to primary immunodeficiency in Crohn's disease.

Authors: Mathias Chamaillard; Rodrigue Dessein
Journal: World J Gastroenterol Date: 2011-02-07 Impact factor: 5.742

4. LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients.

Authors: Ta-Chiang Liu; Takeo Naito; Zhenqiu Liu; Kelli L VanDussen; Talin Haritunians; Dalin Li; Katsuya Endo; Yosuke Kawai; Masao Nagasaki; Yoshitaka Kinouchi; Dermot Pb McGovern; Tooru Shimosegawa; Yoichi Kakuta; Thaddeus S Stappenbeck
Journal: JCI Insight Date: 2017-03-23

5. Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum.

Authors: Amlan Biswas; Yuen-Joyce Liu; Liming Hao; Atsushi Mizoguchi; Nita H Salzman; Charles L Bevins; Koichi S Kobayashi
Journal: Proc Natl Acad Sci U S A Date: 2010-08-02 Impact factor: 11.205

6. Host defense peptide resistance contributes to colonization and maximal intestinal pathology by Crohn's disease-associated adherent-invasive Escherichia coli.

Authors: Joseph B McPhee; Cherrie L Small; Sarah A Reid-Yu; John R Brannon; Hervé Le Moual; Brian K Coombes
Journal: Infect Immun Date: 2014-05-27 Impact factor: 3.441

Decreased Paneth cell defensin expression in ileal Crohn's disease is independent of inflammation, but linked to the NOD2 1007fs genotype.

1. Linkage between genotype and immunological phenotype in Crohn's disease.

2. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.

Review 3. Defensins couple dysbiosis to primary immunodeficiency in Crohn's disease.

4. LRRK2 but not ATG16L1 is associated with Paneth cell defect in Japanese Crohn's disease patients.

5. Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum.

6. Host defense peptide resistance contributes to colonization and maximal intestinal pathology by Crohn's disease-associated adherent-invasive Escherichia coli.

Review 7. Nod2: a key regulator linking microbiota to intestinal mucosal immunity.

8. Muramyl dipeptide and its derivatives: peptide adjuvant in immunological disorders and cancer therapy.

Review 9. Muramyl dipeptide responsive pathways in Crohn's disease: from NOD2 and beyond.

Review 10. Mucosal healing and deep remission: what does it mean?