| Literature DB >> 19432458 |
Toshiaki Teruya1, Hiroaki Sasaki, Kazuhiro Kitamura, Takeshi Nakayama, Kiyotake Suenaga.
Abstract
Bioassay-guided fractionation of the cytotoxic constituents of the marine cyanobacterium Lyngbya sp. led to the isolation of biselyngbyaside (1), a new 18-membered macrolide glycoside. The structure of 1 was established by spectroscopic analysis including 2D-NMR techniques and by synthetic studies. Biselyngbyaside (1) exhibits broad-spectrum cytotoxicity in a human tumor cell line panel.Entities:
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Year: 2009 PMID: 19432458 DOI: 10.1021/ol900579k
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005