Literature DB >> 19432168

[Centrosomal hypothesis of cellular aging and differentiation].

K N Chichinadze, D V Tkemaladze.   

Abstract

The article is dedicated to analysis of centrosomal hypothesis of cellular aging in the light of new data concerning existence of centrosomal RNA, and also in the light of the role of maternal and daughter centrosomes in processes of asymmetric division of stem cells. It is supposed that these data confirm the central role of centrosomes in aging and cellular differentiation. Additional arguments concerning conceptual consistency of telomeric and centrosomal hypothesis of cellular aging are presented.

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Year:  2008        PMID： 19432168

Source DB:  PubMed          Journal:  Adv Gerontol        ISSN： 1561-9125


  2 in total

1.  RNA in centrosomes: structure and possible functions.

Authors:  Konstantin Chichinadze; Ann Lazarashvili; Jaba Tkemaladze
Journal:  Protoplasma       Date:  2012-06-10       Impact factor: 3.356

Review 2.  Gerontology research in Georgia.

Authors:  Teimuraz Lezhava; Jamlet Monaselidze; Tina Jokhadze; Nona Kakauridze; Nodar Khodeli; Mamanti Rogava; Tamara Bochorishvili; Maia Gorgoshidze; Dato Khachidze; Eteri Lomidze; Jaba Tkemaladze; Kote Chichinadze; Marina Koridze; Rusudan Khukhuneishvili; Nato Zosidze; Marina Nagervadze; Tamara Buadze; Maia Gaiozishvili
Journal:  Biogerontology       Date:  2010-05-18       Impact factor: 4.277
  2 in total

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