| Literature DB >> 19431789 |
F R Hallett1, J Watton, P Krygsman.
Abstract
A procedure is described which optimizes nonnegative least squares and exponential sampling fitting methods for analysis of dynamic light scattering (DLS) data from aqueous suspensions of vesicle/liposome systems. This approach utilizes a Rayleigh-Gans-Debye form factor for a coated sphere and yields number distributions which can be compared directly to distributions obtained by freeze-fracture electron microscopy (EM). Excellent agreement between the DLS and EM results are obtained for vesicle size distributions in the 100-200-nm range.Year: 1991 PMID: 19431789 PMCID: PMC1281152 DOI: 10.1016/S0006-3495(91)82229-9
Source DB: PubMed Journal: Biophys J ISSN: 0006-3495 Impact factor: 4.033