Literature DB >> 19431167

Fast attrition-enhanced deracemization of naproxen by a gradual in situ feed.

Wim L Noorduin1, Bernard Kaptein, Hugo Meekes, Willem J P van Enckevort, Richard M Kellogg, Elias Vlieg.   

Abstract

Grind and cure: Using the nonsteroidal anti-inflammatory drug naproxen, a novel concept is demonstrated to dramatically enhance the rate of the recently discovered process of deracemization using abrasive grinding. The process relies on a gradual feed of the racemic target material by an in situ conversion.

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Year:  2009        PMID: 19431167     DOI: 10.1002/anie.200901386

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


  4 in total

1.  Use of a robust dehydrogenase from an archael hyperthermophile in asymmetric catalysis-dynamic reductive kinetic resolution entry into (S)-profens.

Authors:  Jacob A Friest; Yukari Maezato; Sylvain Broussy; Paul Blum; David B Berkowitz
Journal:  J Am Chem Soc       Date:  2010-05-05       Impact factor: 15.419

2.  Enantioselective kinetic resolution of phenylalkyl carboxylic acids using metagenome-derived esterases.

Authors:  Elena Fernández-Álvaro; Robert Kourist; Julia Winter; Dominique Böttcher; Klaus Liebeton; Christian Naumer; Jürgen Eck; Christian Leggewie; Karl-Erich Jaeger; Wolfgang Streit; Uwe T Bornscheuer
Journal:  Microb Biotechnol       Date:  2009-08-05       Impact factor: 5.813

3.  Influence of Ostwald's Rule of Stages in the Deracemization of a Compound Using a Racemic Resolving Agent.

Authors:  Tharit Lerdwiriyanupap; Giuseppe Belletti; Paul Tinnemans; Ruel Cedeno; Hugo Meekes; Elias Vlieg; Adrian E Flood
Journal:  Cryst Growth Des       Date:  2022-01-24       Impact factor: 4.076

4.  Photoracemization-Based Viedma Ripening of a BINOL Derivative.

Authors:  Giuseppe Belletti; Carola Tortora; Indradevi D Mellema; Paul Tinnemans; Hugo Meekes; Floris P J T Rutjes; Svetlana B Tsogoeva; Elias Vlieg
Journal:  Chemistry       Date:  2019-12-12       Impact factor: 5.236

  4 in total

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