Literature DB >> 19430936

A sore throat--potentially life-threatening?

Hai-Yan Li1, Mandy Grubb, Mukta Panda, Roger Jones.   

Abstract

A sore throat, which is most commonly viewed as a minor ailment, can be a manifestation of a life-threatening disorder known as Lemierre's syndrome caused by Fusobacterium necrophorum. We report a new case of Lemierre's syndrome that occurred in an otherwise healthy 18-year-old woman, who initially presented with fever and sore throat. The diagnosis was not made until a week later when blood cultures became available. This syndrome should be suspected until proven otherwise in any patient with signs of pharyngitis, a painful swollen neck, and pulmonary symptoms. By presenting this curable, but potentially life-threatening case of Lemierre's syndrome, we hope to increase the awareness of the early clinical manifestations of Lemierre's syndrome and to emphasize the importance of careful physical examination with special attention to the neck. Clinicians should be aware that exclusion of streptococcal infection in a patient with severe tonsillar infection does not exclude a bacterial cause.

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Year:  2009        PMID: 19430936      PMCID: PMC2695513          DOI: 10.1007/s11606-009-1001-1

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  20 in total

1.  Early antibiotic treatment may prevent complete development of Lemierre's syndrome: experience from 2 cases.

Authors:  Y Sherer; J Mishal; O Leibovici
Journal:  Scand J Infect Dis       Date:  2000

2.  Unusual presentation of Lemierre's syndrome due to Fusobacterium nucleatum.

Authors:  Michael D Williams; Caroline A Kerber; Helen F Tergin
Journal:  J Clin Microbiol       Date:  2003-07       Impact factor: 5.948

Review 3.  Lemierre's syndrome: more than a historical curiosa.

Authors:  T Riordan; M Wilson
Journal:  Postgrad Med J       Date:  2004-06       Impact factor: 2.401

Review 4.  The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection.

Authors:  C P Sinave; G J Hardy; P W Fardy
Journal:  Medicine (Baltimore)       Date:  1989-03       Impact factor: 1.889

5.  Lemierre syndrome: usefulness of CT in detection of extensive occult thrombophlebitis.

Authors:  K V Nguyen-Dinh; K Marsot-Dupuch; F Portier; B Lamblin; P Lasjaunias
Journal:  J Neuroradiol       Date:  2002-06       Impact factor: 3.447

6.  Jugular thrombophlebitis complicating bacterial pharyngitis (Lemierre's syndrome).

Authors:  S De Sena; D L Rosenfeld; S Santos; I Keller
Journal:  Pediatr Radiol       Date:  1996

7.  Real-time PCR investigation into the importance of Fusobacterium necrophorum as a cause of acute pharyngitis in general practice.

Authors:  S H Aliyu; R K Marriott; M D Curran; S Parmar; N Bentley; N M Brown; J S Brazier; H Ludlam
Journal:  J Med Microbiol       Date:  2004-10       Impact factor: 2.472

Review 8.  The evolution of Lemierre syndrome: report of 2 cases and review of the literature.

Authors:  Julio A Chirinos; Daniel M Lichtstein; Javier Garcia; Leonardo J Tamariz
Journal:  Medicine (Baltimore)       Date:  2002-11       Impact factor: 1.889

9.  Lemierre syndrome--a forgotten complication of acute tonsillitis.

Authors:  C B Koay; T Heyworth; P Burden
Journal:  J Laryngol Otol       Date:  1995-07       Impact factor: 1.469

10.  Lemierre's syndrome and other disseminated Fusobacterium necrophorum infections in Denmark: a prospective epidemiological and clinical survey.

Authors:  L Hagelskjaer Kristensen; J Prag
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-03-11       Impact factor: 3.267

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  3 in total

1.  Anchors away.

Authors:  Jacqueline Botros; Joseph Rencic; Robert M Centor; Mark C Henderson
Journal:  J Gen Intern Med       Date:  2014-10       Impact factor: 5.128

2.  Just a sore throat? Uncommon causes of significant respiratory disease.

Authors:  Dalia Wahab; Julia Bichard; Anand Shah; Bhupinder Mann
Journal:  BMJ Case Rep       Date:  2013-04-29

3.  Lemierre's syndrome: forgotten, but not absent.

Authors:  Mandreker Bahall; Stanley Giddings; Krishni Bahall
Journal:  BMJ Case Rep       Date:  2017-08-07
  3 in total

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