Literature DB >> 19430885

Modern treatment of cerebral metastases: Integrated Medical Learning(SM) at CNS 2007.

Michael A Vogelbaum1, Anthony L Asher, Douglas Kondziolka, Nicholas M Boulis, Nathan R Selden, Brian L Hoh, Fred G Barker.   

Abstract

INTRODUCTION: Cerebral metastases are a common problem and pose complex treatment decisions, with reference to local control of treated lesions, prevention of new brain metastases, and toxicity of available treatments. At the 2007 Congress of Neurological Surgeons (CNS) Annual Meeting, a novel active learning process, called Integrated Medical Learning(SM), was used to better understand contemporary practice patterns and to monitor the success of education about these critical treatment decisions.
METHODS: CNS members received an electronically distributed premeeting survey and educational materials about single and multiple cerebral metastasis treatment; practice patterns were elicited. At the Annual Meeting, 496 surgeons were polled using handheld devices before and after surgical and radiation oncology expert presentations. Surgeons who had answered premeeting surveys received a second, postmeeting questionnaire.
RESULTS: In the premeeting questionnaire (N = 214), higher current volume of practice, Tumor Section membership, and academic practice predicted more correct answers (P < 0.05 for all). Fifty five percent favored routine whole brain radiotherapy (WBRT) after metastasis resection. Thirty four percent "most often" used radiosurgery to the resection bed; these respondents cited "cognitive changes" in justifying WBRT omission. At the meeting, expert presentations were followed by audience shifts toward adjuvant WBRT after resection (P = 0.01) or radiosurgery (P < 0.001)-topics for which class I evidence was discussed. There was no shift in preference for surgery or radiosurgery (P = 0.24) or multiple metastasis treatment (P = 0.8)-topics for which clear class I evidence was not presented. Postmeeting questionnaires showed retained knowledge among meeting attendees.
CONCLUSIONS: Using IML, we were able to study baseline knowledge and practice patterns for an important neuro-oncological treatment decision. Evidence suggested expert presentations were effective in changing audience opinion when relevant class I evidence was presented, and that knowledge was retained postmeeting.

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Year:  2009        PMID: 19430885     DOI: 10.1007/s11060-009-9833-4

Source DB:  PubMed          Journal:  J Neurooncol        ISSN: 0167-594X            Impact factor:   4.130


  63 in total

Review 1.  Brain metastases.

Authors:  Mark E Shaffrey; Melike Mut; Anthony L Asher; Stuart H Burri; Ali Chahlavi; Susan M Chang; Elana Farace; John B Fiveash; Frederick F Lang; M Beatriz S Lopes; James M Markert; David Schiff; Vitaly Siomin; Stephen B Tatter; Michael A Vogelbaum
Journal:  Curr Probl Surg       Date:  2004-08       Impact factor: 1.909

Review 2.  The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for brain metastases.

Authors:  Minesh P Mehta; May N Tsao; Timothy J Whelan; David E Morris; James A Hayman; John C Flickinger; Michael Mills; C Leland Rogers; Luis Souhami
Journal:  Int J Radiat Oncol Biol Phys       Date:  2005-09-01       Impact factor: 7.038

3.  Neurocognitive function of patients with brain metastasis who received either whole brain radiotherapy plus stereotactic radiosurgery or radiosurgery alone.

Authors:  Hidefumi Aoyama; Masao Tago; Norio Kato; Tatsuya Toyoda; Masahiro Kenjyo; Saeko Hirota; Hiroki Shioura; Taisuke Inomata; Etsuo Kunieda; Kazushige Hayakawa; Keiichi Nakagawa; Gen Kobashi; Hiroki Shirato
Journal:  Int J Radiat Oncol Biol Phys       Date:  2007-08-01       Impact factor: 7.038

4.  Prospective study of stereotactic radiosurgery without whole brain radiotherapy in patients with four or less brain metastases: incidence of intracranial progression and salvage radiotherapy.

Authors:  Imjai Chitapanarux; Bryan Goss; Roy Vongtama; Leonardo Frighetto; Antonio De Salles; Michael Selch; Michael Duick; Timothy Solberg; Robert Wallace; Cynthia Cabatan-Awang; Judith Ford
Journal:  J Neurooncol       Date:  2003-01       Impact factor: 4.130

Review 5.  Radiotherapeutic management of brain metastases: a systematic review and meta-analysis.

Authors:  May N Tsao; Nancy S Lloyd; Rebecca K S Wong; Eileen Rakovitch; Edward Chow; Normand Laperriere
Journal:  Cancer Treat Rev       Date:  2005-06       Impact factor: 12.111

6.  Management of solitary metastasis to the brain: the role of elective brain irradiation following complete surgical resection.

Authors:  D E Dosoretz; P H Blitzer; A H Russell; C C Wang
Journal:  Int J Radiat Oncol Biol Phys       Date:  1980-12       Impact factor: 7.038

Review 7.  Whole brain radiotherapy for the treatment of multiple brain metastases.

Authors:  M N Tsao; N Lloyd; R Wong; E Chow; E Rakovitch; N Laperriere
Journal:  Cochrane Database Syst Rev       Date:  2006-07-19

8.  Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma.

Authors:  Johanna C Bendell; Susan M Domchek; Harold J Burstein; Lyndsay Harris; Jerry Younger; Irene Kuter; Craig Bunnell; Montse Rue; Rebecca Gelman; Eric Winer
Journal:  Cancer       Date:  2003-06-15       Impact factor: 6.860

9.  Stereotactic radiosurgery without radiation therapy providing high local tumor control of multiple brain metastases from renal cell carcinoma.

Authors:  A Muacevic; F W Kreth; A Mack; J-C Tonn; B Wowra
Journal:  Minim Invasive Neurosurg       Date:  2004-08

10.  Tumor bed radiosurgery after resection of cerebral metastases.

Authors:  David Mathieu; Douglas Kondziolka; John C Flickinger; David Fortin; Brendan Kenny; Karine Michaud; Sanjay Mongia; Ajay Niranjan; L Dade Lunsford
Journal:  Neurosurgery       Date:  2008-04       Impact factor: 4.654

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  1 in total

1.  Therapeutic effect of gamma knife radiosurgery for multiple brain metastases.

Authors:  Chul-Kyu Lee; Sang Ryul Lee; Jin Mo Cho; Kyung Ah Yang; Se-Hyuk Kim
Journal:  J Korean Neurosurg Soc       Date:  2011-09-30
  1 in total

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