Literature DB >> 19429220

Effects of d-amphetamine on behavior maintained by signaled and unsignaled delays to reinforcement.

Lee D Thomas1, Christine E Hughes, Raymond C Pitts.   

Abstract

Four pigeons responded under a progressive-delay procedure. In a signaled-delay condition, a chained variable interval (VI) 30-s progressive time (PT) 4-s schedule was arranged; in an unsignaled-delay condition, a tandem VI 30-s PT 4-s schedule was arranged. Two pigeons experienced a signaled-unsignaled-signaled sequence; whereas, two pigeons experienced an unsignaled-signaled-unsignaled sequence. Effects of saline and d-amphetamine were determined under each condition. At intermediate doses (1.0 and 1.78m/kg) delay functions were shallower, area under the curve was increased, and, when possible, break points were increased compared to saline; these effects were not systematically related to signaling conditions. These effects on control by delay often were accompanied by decreased response rates at 0s. These results suggest that stimulus conditions associated with the delay may not play a crucial role in effects of d-amphetamine and other stimulants on behavior controlled by reinforcement delay.

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Year:  2009        PMID: 19429220     DOI: 10.1016/j.beproc.2009.01.003

Source DB:  PubMed          Journal:  Behav Processes        ISSN: 0376-6357            Impact factor:   1.777


  1 in total

1.  Methylphenidate and impulsivity: a comparison of effects of methylphenidate enantiomers on delay discounting in rats.

Authors:  Jonathan M Slezak; George A Ricaurte; Ronald J Tallarida; Jonathan L Katz
Journal:  Psychopharmacology (Berl)       Date:  2013-08-24       Impact factor: 4.530

  1 in total

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