Literature DB >> 19428436

Biotransformation of methyl cholate by Aspergillus niger.

Amal Al-Aboudi1, Mohammad Y Mohammad, Salim Haddad, Rawhi Al-Far, M Iqbal Choudhary.   

Abstract

Biotransformation of methyl cholate using Aspergillus niger was investigated. This led to the isolation of two derivatives: methyl 3alpha,7alpha,12alpha,15beta-tetrahydroxy-5beta-cholan-24-oate identified as a new compound, and a known compound methyl 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholan-24-oate. The structure elucidation of the new compound was achieved using 1D and 2D NMR, MS and X-ray diffraction.

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Year:  2009        PMID: 19428436     DOI: 10.1016/j.steroids.2009.01.002

Source DB:  PubMed          Journal:  Steroids        ISSN: 0039-128X            Impact factor:   2.668


  3 in total

1.  Synthesis of some potent immunomodulatory and anti-inflammatory metabolites by fungal transformation of anabolic steroid oxymetholone.

Authors:  Naik Tameen Khan; Marium Bibi; Sammer Yousuf; Izhar Husain Qureshi; Null Atta-Ur-Rahman; Abdullah Mohammad Al-Majid; Muhammad Ahmed Mesaik; Ahmed Shukralla Khalid; Samina A Sattar; Null Atia-Tul-Wahab; M Iqbal Choudhary
Journal:  Chem Cent J       Date:  2012-12-10       Impact factor: 4.215

2.  Microbial transformation of anti-cancer steroid exemestane and cytotoxicity of its metabolites against cancer cell lines.

Authors:  Elias Baydoun; Marium Bibi; Muhammad Asif Iqbal; Atia-Tul Wahab; Dina Farran; Colon Smith; Samina A Sattar; Atta-Ur Rahman; M Iqbal Choudhary
Journal:  Chem Cent J       Date:  2013-03-27       Impact factor: 4.215

Review 3.  Microbial Biotransformation to Obtain New Antifungals.

Authors:  Luiz F Bianchini; Maria F C Arruda; Sergio R Vieira; Patrícia M S Campelo; Ana M T Grégio; Edvaldo A R Rosa
Journal:  Front Microbiol       Date:  2015-12-24       Impact factor: 5.640

  3 in total

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