Literature DB >> 19428274

Diagnosis, genetic control and preventive management of canine hip dysplasia: a review.

M M D Ginja1, A M Silvestre, J M Gonzalo-Orden, A J A Ferreira.   

Abstract

Despite expensive screening and breeding programmes, hip dysplasia (HD) continues to be one of the most common orthopaedic diseases in dogs. The vast majority of dogs afflicted with HD show minimal to no clinical signs, but it can also be a highly debilitating condition for both working and pet dogs. Hip joint laxity is considered a major risk factor for the development of degenerative joint disease and a definitive diagnosis is made if characteristic signs are evident on a ventrodorsal view of the pelvis. Early prediction of the condition can be made using stress radiographic techniques to evaluate the passive hip laxity. The diagnosis of HD may be used for the purpose of selecting breeding stock or to decide on the best treatment approach. Breeding programmes based on individual dog phenotypes have been ineffective and a selection procedure based on breeding value (BV) estimation is recommended. Traditional conservative and surgical treatment approaches are reserved for dogs with overt clinical signs of the disease but such treatments can be expensive and aggressive, and are often ineffective in eliminating clinical signs or subluxation and in preventing the development of degenerative joint disease. The implementation of breeding programmes based on BVs and further research into early prediction/diagnosis of HD and effective preventive treatment approaches are essential. Copyright 2009 Elsevier Ltd. All rights reserved.

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Year:  2009        PMID: 19428274     DOI: 10.1016/j.tvjl.2009.04.009

Source DB:  PubMed          Journal:  Vet J        ISSN: 1090-0233            Impact factor:   2.688


  17 in total

1.  Monitoring Hip and Elbow Dysplasia achieved modest genetic improvement of 74 dog breeds over 40 years in USA.

Authors:  Yali Hou; Yachun Wang; Xuemei Lu; Xu Zhang; Qian Zhao; Rory J Todhunter; Zhiwu Zhang
Journal:  PLoS One       Date:  2013-10-04       Impact factor: 3.240

2.  Heritability and phenotypic variation of canine hip dysplasia radiographic traits in a cohort of Australian German shepherd dogs.

Authors:  Bethany J Wilson; Frank W Nicholas; John W James; Claire M Wade; Imke Tammen; Herman W Raadsma; Kao Castle; Peter C Thomson
Journal:  PLoS One       Date:  2012-06-27       Impact factor: 3.240

3.  Spontaneous and bilateral necrosis of the femoral head in a young experimental beagle dog.

Authors:  Ryosuke Kobayashi; Tetsuro Kurotaki; Naoaki Yamada; Shino Kumabe; Takuya Doi; Yumi Wako; Minoru Tsuchitani
Journal:  J Toxicol Pathol       Date:  2015-03-01       Impact factor: 1.628

4.  Hip joint replacement using monofilament polypropylene surgical mesh: an animal model.

Authors:  Jacek Białecki; Marian Majchrzycki; Antoni Szymczak; Małgorzata Dorota Klimowicz-Bodys; Edward Wierzchoś; Krzysztof Kołomecki
Journal:  Biomed Res Int       Date:  2014-05-29       Impact factor: 3.411

5.  Efficacy of an oral hyaluronate and collagen supplement as a preventive treatment of elbow dysplasia.

Authors:  Simón Martí-Angulo; Núria García-López; Ana Díaz-Ramos
Journal:  J Vet Sci       Date:  2014-09-17       Impact factor: 1.672

6.  A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches.

Authors:  Nerea Bartolomé; Sergi Segarra; Marta Artieda; Olga Francino; Elisenda Sánchez; Magdalena Szczypiorska; Joaquim Casellas; Diego Tejedor; Joaquín Cerdeira; Antonio Martínez; Alfonso Velasco; Armand Sánchez
Journal:  PLoS One       Date:  2015-04-13       Impact factor: 3.240

7.  Long-term genetic selection reduced prevalence of hip and elbow dysplasia in 60 dog breeds.

Authors:  A M Oberbauer; G G Keller; T R Famula
Journal:  PLoS One       Date:  2017-02-24       Impact factor: 3.240

8.  Comparative analyses of genetic trends and prospects for selection against hip and elbow dysplasia in 15 UK dog breeds.

Authors:  Thomas W Lewis; Sarah C Blott; John A Woolliams
Journal:  BMC Genet       Date:  2013-03-02       Impact factor: 2.797

9.  A retrospective study on findings of canine hip dysplasia screening in Kenya.

Authors:  Peter Kimeli; Susan W Mbugua; Roger M Cap; Gilbert Kirui; Tequiero O Abuom; Willy E Mwangi; Ambrose N Kipyegon; John D Mande
Journal:  Vet World       Date:  2015-11-22

Review 10.  Diagnosis, prevention, and management of canine hip dysplasia: a review.

Authors:  Emma R Schachner; Mandi J Lopez
Journal:  Vet Med (Auckl)       Date:  2015-05-19
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