PURPOSE: Most studies of quality of life (QOL) in seizure-free epilepsy patients suggest normal or near-normal function. Previous studies on QOL in well-controlled epilepsy have not investigated determinants for QOL from a database that includes a wide range of health related and epilepsy related variables, as well as demographical data, neuropsychological data, data from a comprehensive personality inventory and results from a QOL-questionnaire. Thus, the aim of this study was to analyze predictors of QOL based on such a range of variables. METHODS: Adults with epilepsy on antiepileptic (AED) monotherapy and without epileptic seizures for at least 2 years (n=158) were assessed with the QOLIE-89. RESULTS: The main findings were that QOL in well-controlled epilepsy patients was in the normal range and that presence of substantial health related concerns was a significant predictor of poor QOL. DISCUSSION: The findings that substantial health concerns predict poor QOL may have clinical implications, as seizure-free epilepsy is a relatively benign condition, and careful information and counselling about this may alleviate health concerns and improve quality of life.
PURPOSE: Most studies of quality of life (QOL) in seizure-free epilepsypatients suggest normal or near-normal function. Previous studies on QOL in well-controlled epilepsy have not investigated determinants for QOL from a database that includes a wide range of health related and epilepsy related variables, as well as demographical data, neuropsychological data, data from a comprehensive personality inventory and results from a QOL-questionnaire. Thus, the aim of this study was to analyze predictors of QOL based on such a range of variables. METHODS: Adults with epilepsy on antiepileptic (AED) monotherapy and without epilepticseizures for at least 2 years (n=158) were assessed with the QOLIE-89. RESULTS: The main findings were that QOL in well-controlled epilepsypatients was in the normal range and that presence of substantial health related concerns was a significant predictor of poor QOL. DISCUSSION: The findings that substantial health concerns predict poor QOL may have clinical implications, as seizure-free epilepsy is a relatively benign condition, and careful information and counselling about this may alleviate health concerns and improve quality of life.
Authors: Christianne N Heck; David King-Stephens; Andrew D Massey; Dileep R Nair; Barbara C Jobst; Gregory L Barkley; Vicenta Salanova; Andrew J Cole; Michael C Smith; Ryder P Gwinn; Christopher Skidmore; Paul C Van Ness; Gregory K Bergey; Yong D Park; Ian Miller; Eric Geller; Paul A Rutecki; Richard Zimmerman; David C Spencer; Alica Goldman; Jonathan C Edwards; James W Leiphart; Robert E Wharen; James Fessler; Nathan B Fountain; Gregory A Worrell; Robert E Gross; Stephan Eisenschenk; Robert B Duckrow; Lawrence J Hirsch; Carl Bazil; Cormac A O'Donovan; Felice T Sun; Tracy A Courtney; Cairn G Seale; Martha J Morrell Journal: Epilepsia Date: 2014-02-22 Impact factor: 5.864
Authors: Dileep R Nair; Kenneth D Laxer; Peter B Weber; Anthony M Murro; Yong D Park; Gregory L Barkley; Brien J Smith; Ryder P Gwinn; Michael J Doherty; Katherine H Noe; Richard S Zimmerman; Gregory K Bergey; William S Anderson; Christianne Heck; Charles Y Liu; Ricky W Lee; Toni Sadler; Robert B Duckrow; Lawrence J Hirsch; Robert E Wharen; William Tatum; Shraddha Srinivasan; Guy M McKhann; Mark A Agostini; Andreas V Alexopoulos; Barbara C Jobst; David W Roberts; Vicenta Salanova; Thomas C Witt; Sydney S Cash; Andrew J Cole; Gregory A Worrell; Brian N Lundstrom; Jonathan C Edwards; Jonathan J Halford; David C Spencer; Lia Ernst; Christopher T Skidmore; Michael R Sperling; Ian Miller; Eric B Geller; Michel J Berg; A James Fessler; Paul Rutecki; Alica M Goldman; Eli M Mizrahi; Robert E Gross; Donald C Shields; Theodore H Schwartz; Douglas R Labar; Nathan B Fountain; W Jeff Elias; Piotr W Olejniczak; Nicole R Villemarette-Pittman; Stephan Eisenschenk; Steven N Roper; Jane G Boggs; Tracy A Courtney; Felice T Sun; Cairn G Seale; Kathy L Miller; Tara L Skarpaas; Martha J Morrell Journal: Neurology Date: 2020-07-20 Impact factor: 9.910