Literature DB >> 19427775

Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: a pilot study.

Ali Shamsa1, Hossein Hosseinzadeh, Mahmood Molaei, Mohammad Taghi Shakeri, Omid Rajabi.   

Abstract

In this study, the effect of Crocus sativus (saffron) was studied on male erectile dysfunction (ED). Twenty male patients with ED were followed for ten days in which each morning they took a tablet containing 200mg of saffron. Patients underwent the nocturnal penile tumescence (NPT) test and the international index of erectile function questionnaire (IIEF-15) at the start of the treatment and at the end of the ten days. After the ten days of taking saffron there was a statistically significant improvement in tip rigidity and tip tumescence as well as base rigidity and base tumescence. ILEF-15 total scores were significantly higher in patients after saffron treatment (before treatment 22.15+/-1.44; after treatment 39.20+/-1.90, p<0.001). Saffron showed a positive effect on sexual function with increased number and duration of erectile events seen in patients with ED even only after taking it for ten days.

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Year:  2009        PMID: 19427775     DOI: 10.1016/j.phymed.2009.03.008

Source DB:  PubMed          Journal:  Phytomedicine        ISSN: 0944-7113            Impact factor:   5.340


  22 in total

Review 1.  Pharmacokinetic Properties of Saffron and its Active Components.

Authors:  Azar Hosseini; Bibi Marjan Razavi; Hossein Hosseinzadeh
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2018-08       Impact factor: 2.441

2.  Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial.

Authors:  Amirhossein Modabbernia; Hamid Sohrabi; Abbas-Ali Nasehi; Firoozeh Raisi; Sepideh Saroukhani; Amirhossein Jamshidi; Mina Tabrizi; Mandana Ashrafi; Shahin Akhondzadeh
Journal:  Psychopharmacology (Berl)       Date:  2012-05-03       Impact factor: 4.530

Review 3.  A systematic review of randomized controlled trials examining the effectiveness of saffron (Crocus sativus L.) on psychological and behavioral outcomes.

Authors:  Heather Ann Hausenblas; Kacey Heekin; Heather Lee Mutchie; Stephen Anton
Journal:  J Integr Med       Date:  2015-07

Review 4.  News and future perspectives of non-surgical treatments for erectile dysfunction.

Authors:  Celeste Manfredi; Fabio Castiglione; Mikkel Fode; Michal Lew-Starowicz; Javier Romero-Otero; Carlo Bettocchi; Giovanni Corona
Journal:  Int J Impot Res       Date:  2022-07-27       Impact factor: 2.408

5.  Herbal Dietary Supplements for Erectile Dysfunction: A Systematic Review and Meta-Analysis.

Authors:  Francesca Borrelli; Cristiano Colalto; Domenico V Delfino; Marcello Iriti; Angelo A Izzo
Journal:  Drugs       Date:  2018-04       Impact factor: 9.546

Review 6.  Saffron as an antidote or a protective agent against natural or chemical toxicities.

Authors:  Bibi Marjan Razavi; Hossein Hosseinzadeh
Journal:  Daru       Date:  2015-05-01       Impact factor: 3.117

7.  Safety Evaluation of Crocin (a constituent of saffron) Tablets in Healthy Volunteers.

Authors:  Amir Houshang Mohamadpour; Zahara Ayati; Mohammad-Reza Parizadeh; Omid Rajbai; Hossein Hosseinzadeh
Journal:  Iran J Basic Med Sci       Date:  2013-01       Impact factor: 2.699

8.  Safranal: from an aromatic natural product to a rewarding pharmacological agent.

Authors:  Ramin Rezaee; Hossein Hosseinzadeh
Journal:  Iran J Basic Med Sci       Date:  2013-01       Impact factor: 2.699

9.  Development and Validation of HPLC Method for Determination of Crocetin, a constituent of Saffron, in Human Serum Samples.

Authors:  Amir Hooshang Mohammadpour; Mohammad Ramezani; Nasim Tavakoli Anaraki; Bizhan Malaekeh-Nikouei; Sara Amel Farzad; Hossein Hosseinzadeh
Journal:  Iran J Basic Med Sci       Date:  2013-01       Impact factor: 2.699

10.  A survey on saffron in major islamic traditional medicine books.

Authors:  Behjat Javadi; Amirhossein Sahebkar; Seyed Ahmad Emami
Journal:  Iran J Basic Med Sci       Date:  2013-01       Impact factor: 2.699

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