Literature DB >> 19426729

Antidepressant electroconvulsive therapy: mechanism of action, recent advances and limitations.

Angela Merkl1, Isabella Heuser, Malek Bajbouj.   

Abstract

A considerable number of depressive patients do not respond to or remit during pharmacotherapeutical or psychotherapeutical interventions resulting in an increasing interest in non-pharmacological strategies to treat affective disorders. Electroconvulsive therapy (ECT) dates back to the beginning of modern biologic psychiatry and ongoing research has successfully improved efficacy in addition to safety while reducing side effects. Double-blind, randomized, controlled trials have shown powerful interactions between electrode placement (right unilateral, bifrontal, bitemporal) and dosage (relative to seizure threshold) in the efficacy and side effects of ECT. This review aims to summarize current research data on the mechanism of action, efficacy, and recent advances in ECT technique.

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Year:  2009        PMID: 19426729     DOI: 10.1016/j.expneurol.2009.04.027

Source DB:  PubMed          Journal:  Exp Neurol        ISSN: 0014-4886            Impact factor:   5.330


  24 in total

Review 1.  Brain stimulation in psychiatry and its effects on cognition.

Authors:  Kate E Hoy; Paul B Fitzgerald
Journal:  Nat Rev Neurol       Date:  2010-04-06       Impact factor: 42.937

Review 2.  Fundamentals of transcranial electric and magnetic stimulation dose: definition, selection, and reporting practices.

Authors:  Angel V Peterchev; Timothy A Wagner; Pedro C Miranda; Michael A Nitsche; Walter Paulus; Sarah H Lisanby; Alvaro Pascual-Leone; Marom Bikson
Journal:  Brain Stimul       Date:  2011-11-01       Impact factor: 8.955

Review 3.  Strategies for Treatment-Resistant Depression: Lessons Learned from Animal Models.

Authors:  Gislaine Zilli Réus; Airam Barbosa de Moura; Laura Araújo Borba; Helena Mendes Abelaira; João Quevedo
Journal:  Mol Neuropsychiatry       Date:  2019-05-21

Review 4.  Neurological diseases and pain.

Authors:  David Borsook
Journal:  Brain       Date:  2011-11-08       Impact factor: 13.501

5.  Electroconvulsive therapy: How modern techniques improve patient outcomes: Refinements have decreased memory loss, other adverse effects while retaining efficacy: Refinements have decreased memory loss, other adverse effects while retaining efficacy.

Authors:  Owais Tirmizi; Ahmad Raza; Kenneth Trevino; Mustafa M Husain
Journal:  Curr Psychiatr       Date:  2012-10

6.  Focus on ECT seizure quality: serum BDNF as a peripheral biomarker in depressed patients.

Authors:  Jan Malte Bumb; Suna Su Aksay; Christoph Janke; Laura Kranaster; Olga Geisel; Peter Gass; Rainer Hellweg; Alexander Sartorius
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2014-09-18       Impact factor: 5.270

Review 7.  Amygdala real-time functional magnetic resonance imaging neurofeedback for major depressive disorder: A review.

Authors:  Kymberly D Young; Vadim Zotev; Raquel Phillips; Masaya Misaki; Wayne C Drevets; Jerzy Bodurka
Journal:  Psychiatry Clin Neurosci       Date:  2018-05-21       Impact factor: 5.188

Review 8.  Pharmacologic approaches to treatment resistant depression: a re-examination for the modern era.

Authors:  Noah S Philip; Linda L Carpenter; Audrey R Tyrka; Lawrence H Price
Journal:  Expert Opin Pharmacother       Date:  2010-04       Impact factor: 3.889

9.  Resting-state functional connectivity modulation and sustained changes after real-time functional magnetic resonance imaging neurofeedback training in depression.

Authors:  Han Yuan; Kymberly D Young; Raquel Phillips; Vadim Zotev; Masaya Misaki; Jerzy Bodurka
Journal:  Brain Connect       Date:  2014-11

Review 10.  Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with depression.

Authors:  Peng Lihua; Min Su; Wei Ke; Patrick Ziemann-Gimmel
Journal:  Cochrane Database Syst Rev       Date:  2014-04-11
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