Literature DB >> 19426118

New antifungal therapies for the treatment of onychomycosis.

Sandeep Kumar1, Alexa B Kimball.   

Abstract

Onychomycosis is a common disorder of nails caused by diverse spectrum of fungi ranging from dermatophytes to nondermatophyte molds and yeasts. Presently, oral and topical therapies are the mainstay of treatment with oral therapies yielding somewhat better results. Though various treatment options are available to treat onychomycosis, search for a convenient, cost effective agent with high and long-lasting cure rates is continuing. Currently, many new therapies for onychomycosis are under investigation which includes new formulations of azoles, improvement of existing topical treatments through addition of ungual enhancers and new drugs with better nail permeation

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Year:  2009        PMID: 19426118     DOI: 10.1517/13543780902810352

Source DB:  PubMed          Journal:  Expert Opin Investig Drugs        ISSN: 1354-3784            Impact factor:   6.206


  8 in total

1.  Microemulsion-based antifungal gel delivery to nail for the treatment of onychomycosis: formulation, optimization, and efficacy studies.

Authors:  Bhavesh S Barot; Punit B Parejiya; Hetal K Patel; Dharmik M Mehta; Pragna K Shelat
Journal:  Drug Deliv Transl Res       Date:  2012-12       Impact factor: 4.617

2.  Silicon phthalocyanine 4 phototoxicity in Trichophyton rubrum.

Authors:  Minh Lam; Matthew L Dimaano; Patricia Oyetakin-White; Mauricio A Retuerto; Jyotsna Chandra; Pranab K Mukherjee; Mahmoud A Ghannoum; Kevin D Cooper; Elma D Baron
Journal:  Antimicrob Agents Chemother       Date:  2014-03-10       Impact factor: 5.191

3.  Microemulsion-based gel of terbinafine for the treatment of onychomycosis: optimization of formulation using D-optimal design.

Authors:  Bhavesh S Barot; Punit B Parejiya; Hetal K Patel; Mukesh C Gohel; Pragna K Shelat
Journal:  AAPS PharmSciTech       Date:  2011-12-22       Impact factor: 3.246

4.  Concepts and principles of photodynamic therapy as an alternative antifungal discovery platform.

Authors:  Tianhong Dai; Beth B Fuchs; Jeffrey J Coleman; Renato A Prates; Christos Astrakas; Tyler G St Denis; Martha S Ribeiro; Eleftherios Mylonakis; Michael R Hamblin; George P Tegos
Journal:  Front Microbiol       Date:  2012-04-10       Impact factor: 5.640

5.  Recent Patents on Permeation Enhancers for Drug Delivery Through Nails.

Authors:  Tainá Kreutz; Sheila Porto de Matos; Letícia Scherer Koester
Journal:  Recent Pat Drug Deliv Formul       Date:  2019

Review 6.  Novel 1, 2, 4-Triazoles as Antifungal Agents.

Authors:  Zahra Kazeminejad; Mahrokh Marzi; Abolfazl Shiroudi; Seyed Amin Kouhpayeh; Mojtaba Farjam; Elham Zarenezhad
Journal:  Biomed Res Int       Date:  2022-03-22       Impact factor: 3.411

7.  Efinaconazole Topical Solution, 10%, for the Treatment of Mild and Moderate Toenail Onychomycosis.

Authors:  David A Rodriguez
Journal:  J Clin Aesthet Dermatol       Date:  2015-06

Review 8.  Onychomycosis: Potential of Nail Lacquers in Transungual Delivery of Antifungals.

Authors:  Nida Akhtar; Hemlata Sharma; Kamla Pathak
Journal:  Scientifica (Cairo)       Date:  2016-03-30
  8 in total

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