Literature DB >> 19425589

ent-Kaurane diterpenoids from Isodon pharicus.

Yong Zhao1, Jian-Xin Pu, Sheng-Xiong Huang, Li-Sheng Ding, Ying-Li Wu, Xian Li, Li-Bin Yang, Wei-Lie Xiao, Guo-Qiang Chen, Han-Dong Sun.   

Abstract

Phytochemical investigation of the aerial parts of Isodon pharicus led to the isolation of 13 new ent-kaurane diterpenoids, compounds 1-13, together with 12 known analogues (14-25). The structures of the new compounds were determined by means of extensive spectroscopic techniques including interpretation of 1D and 2D NMR spectra. Selected compounds were evaluated for their cytotoxicity against NB4, A549, PC-3, MCF-7, and SH-SY5Y cell lines.

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Year:  2009        PMID: 19425589     DOI: 10.1021/np9000366

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  4 in total

1.  Bufalin Enhances the Cytotoxity of Human Multiple Myeloma Cells H929 to AKT Inhibitor MK2206: The Role of Protein AKT Phosphorylation.

Authors:  He Huang; Xiao-Ji Lin; Ying Lin; Ron-Xin Yao; Mu-Qing He
Journal:  Indian J Hematol Blood Transfus       Date:  2017-09-30       Impact factor: 0.900

2.  ent-Kaurane glycosides from Tricalysia okelensis.

Authors:  Wen-Hui Xu; Melissa Ruth Jacob; Ameeta Kishore Agarwal; Alice Mae Clark; Zong-Suo Liang; Xing-Cong Li
Journal:  Chem Pharm Bull (Tokyo)       Date:  2010-02       Impact factor: 1.645

3.  A New Human Cancer Cell Proliferation Inhibition Sesquiterpene, Dryofraterpene A, from Medicinal Plant Dryopteris fragrans (L.) Schott.

Authors:  Zheng-Chang Zhong; Dan-Dan Zhao; Zhen-Dong Liu; Shuai Jiang; Yan-Long Zhang
Journal:  Molecules       Date:  2017-01-21       Impact factor: 4.411

4.  Targeting poly (ADP-ribose) polymerase partially contributes to bufalin-induced cell death in multiple myeloma cells.

Authors:  He Huang; Yang Cao; Wei Wei; Wei Liu; Shao-Yong Lu; Yu-Bao Chen; Yan Wang; Hua Yan; Ying-Li Wu
Journal:  PLoS One       Date:  2013-06-07       Impact factor: 3.240

  4 in total

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