Literature DB >> 19425382

[Lipofibroadenoma of the thymus].

Takuya Onuki1, K Iguchi, M Inagaki, K Suzuki.   

Abstract

Here we report a case of a rare thymic tumors histologically diagnosed as lipofibroadenoma. The patient was a 32-year-old male who displayed an anterior mediastinal tumor on a chest computed tomography (CT) scan while being treated for pneumonia. The tumor was localized within the thymus, and the diameter was 3 cm. No significant change was observed in the tumor on a CT scan taken 6 months after the 1st scan. Suspecting a thymoma from the CT and magnetic resonance imaging (MRI) findings, we performed a thymothymectomy via a median sternotomy. The histopathological diagnosis was a lipofibroadenoma of the thymus. The findings resembled fibroadenoma of the breast. Lymphocytes were scarce within the tumor with abundant interstitial stroma, and the tumor epithelial cells displayed restiform and dendritic structures. The epithelial cells were mostly negative for Ki-67 immunohistochemical staining. A very small amount of calcification was detected within the tumor using alizarin red staining. Based on the histopathological findings, it was considered to be a benign tumor with little growth potential, and which had been present for a long period of time.

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Year:  2009        PMID: 19425382

Source DB:  PubMed          Journal:  Kyobu Geka        ISSN: 0021-5252


  3 in total

1.  A rare thymoma type presenting as a giant intrathoracic tumor: lipofibroadenoma.

Authors:  Yener Aydin; Sare Sipal; Mine Celik; Omer Araz; Ali Bilal Ulas; Fatih Alper; Atila Eroglu
Journal:  Eurasian J Med       Date:  2012-12

2.  A Rare Thymic Tumor - Lipofibroadenoma - Always a Postoperative Surprise.

Authors:  Ciprian Bolca; Alexandru Has; Andrei Bobocea; Adelina Afetelor; Radu Stoica; Irina Strambu; Ileana Stoicescu; Elena Magheran; Irina Balescu; Nicolae Bacalbasa; Florentina Gherghiceanu; Florentina Furtunescu; Daniel Radavoi; Camelia Diaconu; Cristian Paleru; Ioan Cordos
Journal:  In Vivo       Date:  2021 Nov-Dec       Impact factor: 2.155

Review 3.  Thymofibrolipoma: a case report and review of the literature.

Authors:  Ryu Jokoji; Emiko Tomita
Journal:  Diagn Pathol       Date:  2022-10-12       Impact factor: 3.196

  3 in total

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