PURPOSE: The aim of this study was to describe the prevalence of atherosclerotic plaques based on [(18)F]-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) in a large population characterized by high risk of cardiovascular disease. PROCEDURES: One hundred forty-one patients referred to our department for FDG-PET/CT for suspected lung cancer were re-evaluated for atherosclerotic lesions. Cardiovascular risk factors were analyzed based on patient records. RESULTS: Forty-two percent of the patients had three cardiovascular risk factors or more. Nine percent of all plaques were assessed as active FDG-accumulating plaques, 88% were inactive calcified plaques, and 2% were mixed. The abdominal aorta was the vessel with the highest plaque count. Patients with one risk factor had significantly less active and inactive plaques. CONCLUSIONS: The observed association between the numbers of cardiovascular risk factors and the numbers of FDG-accumulating plaques as well as calcified plaques further supports the validity and value of FDG-PET/CT in the non-invasive identification and characterization of atherosclerotic disease.
PURPOSE: The aim of this study was to describe the prevalence of atherosclerotic plaques based on [(18)F]-fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) in a large population characterized by high risk of cardiovascular disease. PROCEDURES: One hundred forty-one patients referred to our department for FDG-PET/CT for suspected lung cancer were re-evaluated for atherosclerotic lesions. Cardiovascular risk factors were analyzed based on patient records. RESULTS: Forty-two percent of the patients had three cardiovascular risk factors or more. Nine percent of all plaques were assessed as active FDG-accumulating plaques, 88% were inactive calcified plaques, and 2% were mixed. The abdominal aorta was the vessel with the highest plaque count. Patients with one risk factor had significantly less active and inactive plaques. CONCLUSIONS: The observed association between the numbers of cardiovascular risk factors and the numbers of FDG-accumulating plaques as well as calcified plaques further supports the validity and value of FDG-PET/CT in the non-invasive identification and characterization of atherosclerotic disease.
Authors: D Blockmans; L De Ceuninck; S Vanderschueren; D Knockaert; L Mortelmans; H Bobbaers Journal: Rheumatology (Oxford) Date: 2006-11-18 Impact factor: 7.580
Authors: John R Davies; James H F Rudd; Tim D Fryer; Martin J Graves; John C Clark; Peter J Kirkpatrick; Jonathan H Gillard; Elizabeth A Warburton; Peter L Weissberg Journal: Stroke Date: 2005-11-10 Impact factor: 7.914
Authors: Ahmed Tawakol; Raymond Q Migrino; Gregory G Bashian; Shahinaz Bedri; David Vermylen; Ricardo C Cury; Denise Yates; Glenn M LaMuraglia; Karen Furie; Stuart Houser; Henry Gewirtz; James E Muller; Thomas J Brady; Alan J Fischman Journal: J Am Coll Cardiol Date: 2006-10-17 Impact factor: 24.094
Authors: J H F Rudd; E A Warburton; T D Fryer; H A Jones; J C Clark; N Antoun; P Johnström; A P Davenport; P J Kirkpatrick; B N Arch; J D Pickard; P L Weissberg Journal: Circulation Date: 2002-06-11 Impact factor: 29.690
Authors: Nehal N Mehta; YiDing Yu; Babak Saboury; Negar Foroughi; Parasuram Krishnamoorthy; Anna Raper; Amanda Baer; Jules Antigua; Abby S Van Voorhees; Drew A Torigian; Abass Alavi; Joel M Gelfand Journal: Arch Dermatol Date: 2011-05-16
Authors: Sophie J Bernelot Moens; Robert M Stoekenbroek; Fleur M van der Valk; Simone L Verweij; Mark J W Koelemay; Hein J Verberne; Max Nieuwdorp; Erik S G Stroes Journal: BMC Cardiovasc Disord Date: 2016-11-25 Impact factor: 2.298