Literature DB >> 19424670

[Bronchial asthma and chronic obstructive pulmonary disease with acute exacerbation: preclinical differential diagnostic and emergency treatment].

B Friege1, L Friege, J Pelz, M Weber, T von Spiegel, S Schröder.   

Abstract

Chronic obstructive pulmonary disease (COPD) and bronchial asthma are the most common causes of obstructive pulmonary diseases and acute dyspnoea. In the preclinical emergency situation a distinction between bronchial asthma and exacerbated COPD is difficult because symptoms are similar. Although the preclinical measures differ only marginally, a differential diagnosis from other causes of respiratory obstruction and acute dyspnoea, such as cardiac decompensation, anaphylaxis, aspiration of foreign bodies, tension pneumothorax and inhalation trauma is necessary because alternative treatment options are required. In the treatment of COPD and bronchial asthma inhalative bronchodilatory beta(2)-mimetics are the first choice especially for serious obstructive emergencies because there is an unfavorable relationship between effect and side-effects for the intravenous route. Dosable aerosols, nebulization and if necessary, continuous nebulization, are appropriate application forms even for serious obstructive crises with the need of a respirator. In these cases a minimal inspiratory flow in patients is not required. Theophylline only plays a minor role to beta(2)-mimetics and anticholinergics as a bronchodilator in asthma and COPD guidelines, even in serious obstructive diseases. For severe asthma attacks the administration of magnesium is a possible additional option. Systemic intravenous administration of steroids has an anti-inflammatory effect and for this reason is the second column of treatment for both diseases. Invasive ventilation remains a last resort to ensure respiratory function and indications for this are given in patients with clinical signs of impending exhaustion of breathing.

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Year:  2009        PMID: 19424670     DOI: 10.1007/s00101-009-1536-x

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  29 in total

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Journal:  Anaesthesist       Date:  2007-06       Impact factor: 1.041

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8.  Association of noninvasive ventilation with nosocomial infections and survival in critically ill patients.

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Journal:  JAMA       Date:  2000-11-08       Impact factor: 56.272

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Journal:  Chest       Date:  1990-06       Impact factor: 9.410

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Authors:  Enzo Squadrone; Pamela Frigerio; Claudio Fogliati; Cesare Gregoretti; Giorgio Conti; Massimo Antonelli; Roberta Costa; Paola Baiardi; Paolo Navalesi
Journal:  Intensive Care Med       Date:  2004-06-12       Impact factor: 17.440

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  3 in total

1.  [Digitalis and theophylline: old and superfluous?].

Authors:  M Gosch; P Dovjak
Journal:  Z Gerontol Geriatr       Date:  2013-07       Impact factor: 1.281

2.  [Live-threatening bronchospasm during anesthesia induction : when pure routine becomes a nightmare].

Authors:  A Rüggeberg; J Breckwoldt
Journal:  Anaesthesist       Date:  2011-09-16       Impact factor: 1.041

3.  Observation of the Effect of Singulair Combined With Ketotifen in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease With Airway Hyperresponsiveness and Its Influence on Th17/Treg.

Authors:  Haiou Wang; Gaojie Qu
Journal:  Front Surg       Date:  2022-02-28
  3 in total

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