BACKGROUND: In older children, one of the standards for indexing left ventricular mass (LVM) is height raised to an exponential power of 2.7. The purpose of this study was to establish a normal value for the pediatric age group and to determine how, if at all, LVM/height(2.7) varies in children. METHODS: M-mode echocardiography was performed in 2,273 nonobese, healthy children (1,267 boys, 1,006 girls; age range 0-18 years). Curves were constructed for the 5th, 10th, 25th, 50th, 75th, 90th, and 95th quantiles of LVM/height(2.7). RESULTS: In children aged > 9 years, median LVM/height(2.7) ranged from 27 to 32 g/m(2.7) and had little variation with age. However, in those aged < 9 years, LVM/height(2.7) varied significantly, and percentiles for newborns and infants were approximately double the levels for older children and adolescents: the 95th percentile ranged from 80 g/m(2.7) for newborns to 40 g/m(2.7) for 11-year-olds. CONCLUSION: For patients aged > 9 years, quantiles of LVM/height(2.7) vary little, and values > 40 g/m(2.7) in girls and > 45 g/m(2.7) in boys can be considered abnormal (ie, > 95th percentile). However, for patients aged < 9 years, the index varies with age, and therefore, measured LVM/height(2.7) must be compared with percentile curves, which are provided. This variation in LVM/height(2.7) in younger children indicates that a better indexing method is needed for this age group. Nevertheless, these data are valuable in that they provide normal values with which patient data can be compared.
BACKGROUND: In older children, one of the standards for indexing left ventricular mass (LVM) is height raised to an exponential power of 2.7. The purpose of this study was to establish a normal value for the pediatric age group and to determine how, if at all, LVM/height(2.7) varies in children. METHODS: M-mode echocardiography was performed in 2,273 nonobese, healthy children (1,267 boys, 1,006 girls; age range 0-18 years). Curves were constructed for the 5th, 10th, 25th, 50th, 75th, 90th, and 95th quantiles of LVM/height(2.7). RESULTS: In children aged > 9 years, median LVM/height(2.7) ranged from 27 to 32 g/m(2.7) and had little variation with age. However, in those aged < 9 years, LVM/height(2.7) varied significantly, and percentiles for newborns and infants were approximately double the levels for older children and adolescents: the 95th percentile ranged from 80 g/m(2.7) for newborns to 40 g/m(2.7) for 11-year-olds. CONCLUSION: For patients aged > 9 years, quantiles of LVM/height(2.7) vary little, and values > 40 g/m(2.7) in girls and > 45 g/m(2.7) in boys can be considered abnormal (ie, > 95th percentile). However, for patients aged < 9 years, the index varies with age, and therefore, measured LVM/height(2.7) must be compared with percentile curves, which are provided. This variation in LVM/height(2.7) in younger children indicates that a better indexing method is needed for this age group. Nevertheless, these data are valuable in that they provide normal values with which patient data can be compared.
Authors: Abanti Chaudhuri; Scott M Sutherland; Brandy Begin; Kari Salsbery; Lonisa McCabe; Donald Potter; Steven R Alexander; Cynthia J Wong Journal: Clin J Am Soc Nephrol Date: 2011-01-27 Impact factor: 8.237
Authors: Marc B Lande; Donald L Batisky; Juan C Kupferman; Joshua Samuels; Stephen R Hooper; Bonita Falkner; Shari R Waldstein; Peter G Szilagyi; Hongyue Wang; Jennifer Staskiewicz; Heather R Adams Journal: J Pediatr Date: 2018-02-03 Impact factor: 4.406
Authors: Marc B Lande; Donald L Batisky; Juan C Kupferman; Joshua Samuels; Stephen R Hooper; Bonita Falkner; Shari R Waldstein; Peter G Szilagyi; Hongyue Wang; Jennifer Staskiewicz; Heather R Adams Journal: J Pediatr Date: 2016-09-29 Impact factor: 4.406
Authors: Samuel S Gidding; Robert A Palermo; Stephanie S DeLoach; Scott W Keith; Bonita Falkner Journal: Pediatr Cardiol Date: 2013-10-06 Impact factor: 1.655
Authors: A Broomfield; J Fletcher; J Davison; N Finnegan; M Fenton; A Chikermane; C Beesley; K Harvey; E Cullen; C Stewart; S Santra; S Vijay; M Champion; L Abulhoul; S Grunewald; A Chakrapani; M A Cleary; S A Jones; A Vellodi Journal: J Inherit Metab Dis Date: 2015-10-26 Impact factor: 4.982