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Literature DB >> 194227

The sequence specificity of vertebrate DNA methylation.

Abstract

The relative quantity of 5-methyl cytosine in vertebrate nuclear DNA shows species and tissue variation. To determine whether this is due to the action of species or cell specific DNA methylases the sequence specificity of the 5-methyl cytosine distribution in the DNA of a range of cells has been partially characterised. The pattern of methylation was found to be remarkably constant and indicates stringent evolutionary conservation of the characteristics of vertebrate DNA methylation.

Entities: Chemical

Mesh：

Substances：

Year: 1977 PMID： 194227 PMCID： PMC342502 DOI： 10.1093/nar/4.4.1025

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

27 in total

Review 1. X inactivation, differentiation, and DNA methylation.

Authors: A D Riggs
Journal: Cytogenet Cell Genet Date: 1975

2. REGULATION OF GROWTH AND ORIENTATION IN HAMSTER CELLS TRANSFORMED BY POLYOMA VIRUS.

Authors: M STOKER
Journal: Virology Date: 1964-10 Impact factor: 3.616

3. Enzymatic synthesis of deoxyribonucleic acid. XI. Further studies on nearest neighbor base sequences in deoxyribonucleic acids.

Authors: M N SWARTZ; T A TRAUTNER; A KORNBERG
Journal: J Biol Chem Date: 1962-06 Impact factor: 5.157

4. The distribution of nucleotides in deoxyribonucleic acid.

Authors: G B PETERSEN
Journal: Biochem J Date: 1963-06 Impact factor: 3.857

5. Studies on the nucleotide arrangement in deoxyribonucleic acids. VI. Pyrimidine nucleotide clusters: frequency and distribution in several species of the AT-type.

Authors: J H SPENCER; E CHARGAFF
Journal: Biochim Biophys Acta Date: 1963-01-29

The sequence specificity of vertebrate DNA methylation.

Review 1. X inactivation, differentiation, and DNA methylation.

2. REGULATION OF GROWTH AND ORIENTATION IN HAMSTER CELLS TRANSFORMED BY POLYOMA VIRUS.

3. Enzymatic synthesis of deoxyribonucleic acid. XI. Further studies on nearest neighbor base sequences in deoxyribonucleic acids.

4. The distribution of nucleotides in deoxyribonucleic acid.

5. Studies on the nucleotide arrangement in deoxyribonucleic acids. VI. Pyrimidine nucleotide clusters: frequency and distribution in several species of the AT-type.

6. Distribution of 5-methylcytosine in pyrimidine sequences of deoxyribonucleic acids.

7. The occurrence of 6-methylaminopurine in deoxyribonucleic acids.

8. Distribution density of nucleotides within a desoxyribonucleic acid chain.

9. DNA modification mechanisms and gene activity during development.

10. Polyoma transformation of hamster cell clones--an investigation of genetic factors affecting cell competence.

1. Deoxyribonucleic acid methylation and chromatin organization in Tetrahymena thermophila.

2. Methylation of DNA repeats of decreasing sizes in Ascobolus immersus.

3. Methylation of nucleosomal and nuclease sensitive DNA.

4. Methylation of somatic vs germ cell DNAs analyzed by restriction endonuclease digestions.

5. Localization of DNA methyltransferase in the chromatin of Friend erythroleukemia cells.

6. Statistical characterization of nucleic acid sequence functional domains.

7. Polymorphism of 5-methylcytosine-rich DNA in human acrocentric chromosomes.

8. The sequence specificity of a mammalian DNA methylase.

9. The 5'-cytosine in CCGG1 is methylated in two eukaryotic DNAs and Msp I is sensitive to methylation at this site.

10. Interaction of DNA methyltransferase with aminofluorene and N-acetylaminofluorene modified poly(dC-dG).