Literature DB >> 19421436

Non Lewis acid catalysed epoxide ring opening with amino acid esters.

Christine Philippe1, Thierry Milcent, Benoit Crousse, Danièle Bonnet-Delpon.   

Abstract

The ring opening of epoxides by various amino acid esters is described in refluxing trifluoroethanol without any catalyst. Under these simple conditions the corresponding beta-amino alcohols are obtained in good to excellent yields in relatively short reaction times compared to previously reported methods.

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Year:  2009        PMID： 19421436     DOI： 10.1039/b902081k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  3 in total

1.  Stable Isotope-Assisted Metabolomics for Deciphering Xenobiotic Metabolism in Mammalian Cell Culture.

Authors:  Mira Flasch; Christoph Bueschl; Lydia Woelflingseder; Heidi E Schwartz-Zimmermann; Gerhard Adam; Rainer Schuhmacher; Doris Marko; Benedikt Warth
Journal:  ACS Chem Biol       Date:  2020-03-25       Impact factor: 5.100

2.  N,N'-(Hexane-1,6-diyl)bis(4-methyl-N-(oxiran-2-ylmethyl)benzenesulfonamide): Synthesis via cyclodextrin mediated N-alkylation in aqueous solution and further Prilezhaev epoxidation.

Authors:  Julian Fischer; Simon Millan; Helmut Ritter
Journal:  Beilstein J Org Chem       Date:  2013-12-09       Impact factor: 2.883

3.  Oligomeric epoxide-amine adducts based on 2-amino-N-isopropylacetamide and α-amino-ε-caprolactam: Solubility in presence of cyclodextrin and curing properties.

Authors:  Julian Fischer; Helmut Ritter
Journal:  Beilstein J Org Chem       Date:  2013-12-05       Impact factor: 2.883
  3 in total

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