OBJECTIVES: To compare the corneal anterior chamber depth (ACD) adjusted by age and sex in normal and keratoconus eyes. METHODS: Scheimpflug photography with the Oculus Pentacam was used to measure the ACD of 162 normal and 41 keratoconus patients. RESULTS: Univariate analysis showed that the mean ACD of 162 normal subjects (3.18 +/- 0.32 mm) was borderline significantly less than in 41 keratoconus patients (3.28 +/- 0.40 mm; P=0.079). However, we found that sex (P=0.001) and age (P<0.001) are significantly related to ACD in all patients. Women with normal eyes had a significantly lower mean ACD (3.13 +/- 0.34 mm) than men (3.27 +/- 0.28 mm, P=0.008). Women with keratoconus eyes also had a lower mean ACD (3.16 +/- 0.39 mm) than men with keratoconus (3.42 +/- 0.36 mm, P=0.032). Bivariate regression showed that with each additional year of aging, the ACD was decreased by an average of 0.012 mm in a normal eye (P<0.001) and by 0.014 mm in a keratoconus eye (P<0.001). Regression analysis showed that sex (P=0.003), age (P<0.001), and keratoconus (P=0.003) are all significant variables for determining ACD. After adjusting for age and sex, keratoconus eyes had a significantly higher mean ACD (3.34 +/- 0.34 mm) than normal eyes (3.18 +/- 0.28 mm) (P=0.003). CONCLUSIONS: Sex, age, and keratoconus are all significant variables for ACD. After adjusting for age, keratoconus eyes of both genders had a significantly higher ACD than normal eyes of both genders. Women showed lower mean ACD than men in both normal and keratoconus eyes.
OBJECTIVES: To compare the corneal anterior chamber depth (ACD) adjusted by age and sex in normal and keratoconus eyes. METHODS: Scheimpflug photography with the Oculus Pentacam was used to measure the ACD of 162 normal and 41 keratoconus patients. RESULTS: Univariate analysis showed that the mean ACD of 162 normal subjects (3.18 +/- 0.32 mm) was borderline significantly less than in 41 keratoconus patients (3.28 +/- 0.40 mm; P=0.079). However, we found that sex (P=0.001) and age (P<0.001) are significantly related to ACD in all patients. Women with normal eyes had a significantly lower mean ACD (3.13 +/- 0.34 mm) than men (3.27 +/- 0.28 mm, P=0.008). Women with keratoconus eyes also had a lower mean ACD (3.16 +/- 0.39 mm) than men with keratoconus (3.42 +/- 0.36 mm, P=0.032). Bivariate regression showed that with each additional year of aging, the ACD was decreased by an average of 0.012 mm in a normal eye (P<0.001) and by 0.014 mm in a keratoconus eye (P<0.001). Regression analysis showed that sex (P=0.003), age (P<0.001), and keratoconus (P=0.003) are all significant variables for determining ACD. After adjusting for age and sex, keratoconus eyes had a significantly higher mean ACD (3.34 +/- 0.34 mm) than normal eyes (3.18 +/- 0.28 mm) (P=0.003). CONCLUSIONS: Sex, age, and keratoconus are all significant variables for ACD. After adjusting for age, keratoconus eyes of both genders had a significantly higher ACD than normal eyes of both genders. Women showed lower mean ACD than men in both normal and keratoconus eyes.
Authors: Matthew T Feng; Michael W Belin; Renato Ambrósio; Satinder P S Grewal; Wang Yan; Mohamed S Shaheen; Charles McGhee; Naoyuki Maeda; Tobias H Neuhann; H Burkhard Dick; Saleh A Alageel; Andreas Steinmueller Journal: Saudi J Ophthalmol Date: 2011-04-30
Authors: Mohammed Ali Abu Ameerh; Nathalie Bussières; Ghada Ismail Hamad; Muawyah Dawoud Al Bdour Journal: Int J Ophthalmol Date: 2014-08-18 Impact factor: 1.779
Authors: Mariam Lofty Khaled; Yelena Bykhovskaya; Chunfang Gu; Alice Liu; Michelle D Drewry; Zhong Chen; Barbara A Mysona; Emily Parker; Ryan P McNabb; Hongfang Yu; Xiaowen Lu; Jing Wang; Xiaohui Li; Abdulrahman Al-Muammar; Jerome I Rotter; Louise F Porter; Amy Estes; Mitchell A Watsky; Sylvia B Smith; Hongyan Xu; Khaled K Abu-Amero; Anthony Kuo; Stephen B Shears; Yaron S Rabinowitz; Yutao Liu Journal: Sci Rep Date: 2019-12-18 Impact factor: 4.379