Literature DB >> 19420948

Feasibility of buprenorphine maintenance therapy programs in the Ukraine: first promising treatment outcomes.

Michael Schaub1, Emilis Subata, Victor Chtenguelov, Gundo Weiler, Ambros Uchtenhagen.   

Abstract

BACKGROUND: Opiate substitution therapy (OST) in the Ukraine was not provided until 2004. As part of the introduction of OST, the first feasibility study was conducted in 2007. Six clinics in 6 cities were involved in providing OST and collecting data.
METHODS: A total of 151 opiate-dependent patients were given buprenorphine as a substitute, and a survey of substance use, HIV transmission risks, and legal and social status was conducted at baseline and at 6 and 12-month follow-up.
RESULTS: Illegal substance use and illegal activities and incomes were highly reduced, whereas employment rates and psychiatric problems improved. Retention was comparatively high (79.5%) after 12 months. No significant adverse events were reported.
CONCLUSION: A successful implementation of OST in the Ukraine is feasible. Copyright 2009 S. Karger AG, Basel.

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Year:  2009        PMID: 19420948     DOI: 10.1159/000217586

Source DB:  PubMed          Journal:  Eur Addict Res        ISSN: 1022-6877            Impact factor:   3.015


  6 in total

Review 1.  Changes in quality of life (WHOQOL-BREF) and addiction severity index (ASI) among participants in opioid substitution treatment (OST) in low and middle income countries: an international systematic review.

Authors:  Jonathan P Feelemyer; Don C Des Jarlais; Kamyar Arasteh; Benjamin W Phillips; Holly Hagan
Journal:  Drug Alcohol Depend       Date:  2013-10-24       Impact factor: 4.492

Review 2.  Retention of participants in medication-assisted programs in low- and middle-income countries: an international systematic review.

Authors:  Jonathan Feelemyer; Don Des Jarlais; Kamyar Arasteh; Abu S Abdul-Quader; Holly Hagan
Journal:  Addiction       Date:  2013-08-15       Impact factor: 6.526

3.  Geographic variability in HIV and injection drug use in Ukraine: implications for integration and expansion of drug treatment and HIV care.

Authors:  Nickolas Zaller; Alonya Mazhnaya; Sarah Larney; Zahed Islam; Alyona Shost; Tatiana Prokhorova; Natasha Rybak; Timothy Flanigan
Journal:  Int J Drug Policy       Date:  2014-09-16

4.  The real-world impact of dosing of methadone and buprenorphine in retention on opioid agonist therapies in Ukraine.

Authors:  Scott O Farnum; Iuliia Makarenko; Lynn Madden; Alyona Mazhnaya; Ruthanne Marcus; Tanya Prokhorova; Martha J Bojko; Julia Rozanova; Sergii Dvoriak; Zahedsul Islam; Frederick L Altice
Journal:  Addiction       Date:  2020-08-09       Impact factor: 6.526

Review 5.  Opiate substitution treatment and HIV transmission in people who inject drugs: systematic review and meta-analysis.

Authors:  Georgie J MacArthur; Silvia Minozzi; Natasha Martin; Peter Vickerman; Sherry Deren; Julie Bruneau; Louisa Degenhardt; Matthew Hickman
Journal:  BMJ       Date:  2012-10-03

6.  Retention in Georgia opioid substitution therapy program and associated factors.

Authors:  Ekaterine Ruadze; Khatuna Todadze
Journal:  Harm Reduct J       Date:  2016-12-08
  6 in total

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