Literature DB >> 19420872

[Case of double cancer of the liver, cholangiocarcinoma and hepatocellular carcinoma detected in a patient with hepatitis C 13 years after diminution of HCV-RNA by interferon treatment].

Takako Tsumura1, Shintaro Takaki, Hiroshi Aikata, Yuki Kimura, Yoshio Katamura, Takahiro Azakami, Tomokazu Kawaoka, Masataka Tsuge, Hiromi Sanetou, Koji Waki, Akira Hiramatsu, Michio Imamura, Yoshiiku Kawakami, Shoichi Takahashi, Koji Arihiro, Kazuaki Chayama.   

Abstract

A 56-year-old man with chronic hepatitis C (HCV) was treated with interferon therapy and achieved sustained virological response (SVR) in 1993. Thirteen years later, in 2006 two liver tumors, 35-mm and 11-mm in diameter respectively, were detected in liver segment 6. Hepatic resection was performed, and pathologically one nodule was diagnosed as cholangiocellular carcinoma (CCC) and the other hepatocellular carcinoma (HCC). Continuity was not recognized between these tumors, thus, we diagnosed this case as double cancer (CCC and HCC). Here, we report a rare case of double cancer (CCC and HCC) that developed 13 years after achieving SVR for HCV infection.

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Year:  2009        PMID: 19420872

Source DB:  PubMed          Journal:  Nihon Shokakibyo Gakkai Zasshi        ISSN: 0446-6586


  3 in total

1.  Development of a hepatocellular carcinoma in a chronic hepatitis C patient 18 years after achieving a sustained virological response to interferon therapy: case report and literature review.

Authors:  Masaya Saito; Yasushi Seo; Yoshihiko Yano; Akira Miki; Yukiko Morinaga; Tomoo Itoh; Masaru Yoshida; Takeshi Azuma
Journal:  Clin J Gastroenterol       Date:  2012-02-18

2.  Intrahepatic cholangiocellular carcinoma and hepatocellular carcinoma developed after a 6-year sustained virological response to interferon therapy for chronic hepatitis C.

Authors:  Shinji Takashimizu; Sei-Ichiro Kojima; Junko Nagata; Yasuhiro Nishizaki; Tatehiro Kagawa; Koichi Shiraishi; Tetsuya Mine; Jun-Ichi Kaneko; Norihiro Kokudo; Norihito Watanabe
Journal:  Clin J Gastroenterol       Date:  2011-03-24

Review 3.  Occurrence of hepatocellular carcinoma 24 years after successful interferon therapy in a patient with chronic hepatitis C: a case report.

Authors:  Yuichi Yoshida; Miki Yonezawa; Takuya Okamoto; Yudai Fujiwara; Akiko Suzuki; Yuji Suzuki; Kei Endo; Keisuke Kakisaka; Takayoshi Oikawa; Hidekatsu Kuroda; Akio Miyasaka; Yasuhiro Takikawa
Journal:  Clin J Gastroenterol       Date:  2018-10-19
  3 in total

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