Literature DB >> 1942008

Maternal transmission of SIVsmm in rhesus macaques.

H M McClure1, D C Anderson, P N Fultz, A A Ansari, T Jehuda-Cohen, F Villinger, S A Klumpp, W Switzer, E Lockwood, A Brodie.   

Abstract

Fifteen SIV-infected rhesus monkeys delivered 13 livebirths and two stillbirths; one livebirth died at three days of age. While all infants were culture-negative for SIV at birth, nine had maternal antibodies that disappeared by six months of age. Three infants subsequently seroconverted and became virus positive at 9-15 months. Milk samples from all mothers were virus-negative at parturition but samples from four animals were virus-positive at nine and 12 months. This study documents maternal transmission of SIV and suggests transmission by breast-feeding.

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Year:  1991        PMID: 1942008

Source DB:  PubMed          Journal:  J Med Primatol        ISSN: 0047-2565            Impact factor:   0.667


  6 in total

Review 1.  The rhesus macaque pediatric SIV infection model - a valuable tool in understanding infant HIV-1 pathogenesis and for designing pediatric HIV-1 prevention strategies.

Authors:  Kristina Abel
Journal:  Curr HIV Res       Date:  2009-01       Impact factor: 1.581

Review 2.  Pathogenesis of human immunodeficiency virus infection.

Authors:  J A Levy
Journal:  Microbiol Rev       Date:  1993-03

Review 3.  Immunology of pediatric HIV infection.

Authors:  Nicole H Tobin; Grace M Aldrovandi
Journal:  Immunol Rev       Date:  2013-07       Impact factor: 12.988

4.  Feline immunodeficiency virus can be experimentally transmitted via milk during acute maternal infection.

Authors:  R K Sellon; H L Jordan; S Kennedy-Stoskopf; M B Tompkins; W A Tompkins
Journal:  J Virol       Date:  1994-05       Impact factor: 5.103

5.  Exposure to SIV in utero results in reduced viral loads and altered responsiveness to postnatal challenge.

Authors:  Chris A R Baker; Louise Swainson; Din L Lin; Samson Wong; Dennis J Hartigan-O'Connor; Jeffrey D Lifson; Alice F Tarantal; Joseph M McCune
Journal:  Sci Transl Med       Date:  2015-08-12       Impact factor: 17.956

6.  Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.

Authors:  Ann Chahroudi; Emily Cartwright; S Thera Lee; Maud Mavigner; Diane G Carnathan; Benton Lawson; Paul M Carnathan; Tayebeh Hashempoor; Megan K Murphy; Tracy Meeker; Stephanie Ehnert; Christopher Souder; James G Else; Joyce Cohen; Ronald G Collman; Thomas H Vanderford; Sallie R Permar; Cynthia A Derdeyn; Francois Villinger; Guido Silvestri
Journal:  PLoS Pathog       Date:  2014-03-06       Impact factor: 6.823

  6 in total

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