Literature DB >> 19418525

Application of copper(II)-dipyridylphosphine catalyst in the asymmetric hydrosilylation of simple ketones in air.

Xi-Chang Zhang1, Yan Wu, Feng Yu, Fei-Fei Wu, Jing Wu, Albert S C Chan.   

Abstract

Ask a copper: A copper(II) salt/chiral dipyridylphosphine/PhSiH(3) system (see scheme) acts as a very effective and practical catalyst for the asymmetric reduction of heteroaromatic and other types of ketones in air with good-to-excellent enantioselectivities (up to 94%), giving many chiral alcohols that are intermediates for physiologically active compounds. Remarkable temperature effects were observed for some heteroaromatic ketones.

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Year:  2009        PMID： 19418525     DOI： 10.1002/chem.200900499

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  4 in total

1.  Concise methods for the synthesis of chiral polyoxazolines and their application in asymmetric hydrosilylation.

Authors:  Wei Jie Li; Zun Le Xu; Sheng Xiang Qiu
Journal:  Beilstein J Org Chem       Date:  2010-03-25       Impact factor: 2.883

2.  Rh(I)-bisphosphine-catalyzed asymmetric, intermolecular hydroheteroarylation of α-substituted acrylate derivatives.

Authors:  Claire M Filloux; Tomislav Rovis
Journal:  J Am Chem Soc       Date:  2014-12-29       Impact factor: 15.419

3.  A supramolecularly tunable chiral diphosphine ligand: application to Rh and Ir-catalyzed enantioselective hydrogenation.

Authors:  Xi-Chang Zhang; Yi-Hu Hu; Chuan-Fu Chen; Qiang Fang; Li-Yao Yang; Ying-Bo Lu; Lin-Jie Xie; Jing Wu; Shijun Li; Wenjun Fang
Journal:  Chem Sci       Date:  2016-03-31       Impact factor: 9.825

4.  Manganese-Catalyzed Asymmetric Hydrosilylation of Aryl Ketones.

Authors:  Xiaochen Ma; Ziqing Zuo; Guixia Liu; Zheng Huang
Journal:  ACS Omega       Date:  2017-08-18
  4 in total

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