Literature DB >> 1941836

Pneumocystis carinii pneumonia associated with methotrexate therapy in rheumatoid arthritis.

D A Flood1, C K Chan, W Pruzanski.   

Abstract

Opportunistic infections occur in patients with rheumatic diseases treated with low dose methotrexate (MTX) with or without other immunosuppressants. Our case report illustrates a fatal case of Pneumocystis carinii pneumonia in a patient with rheumatoid arthritis treated with low dose MTX and glucocorticoid. A review of the literature reveals other opportunistic infections such as Cryptococcus, Nocardia, and herpes zoster presenting in such patients. These occurrences suggest that MTX should be used cautiously in patients with rheumatic disease receiving concomitant medical therapy.

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Year:  1991        PMID： 1941836

Source DB:  PubMed          Journal:  J Rheumatol        ISSN： 0315-162X            Impact factor:   4.666


  6 in total

Review 1.  Methotrexate-related pulmonary complications in rheumatoid arthritis.

Authors:  P Barrera; R F Laan; P L van Riel; P N Dekhuijzen; A M Boerbooms; L B van de Putte
Journal:  Ann Rheum Dis       Date:  1994-07       Impact factor: 19.103

2.  Factors Associated with Pneumocystis jirovecii Pneumonia in Patients with Rheumatoid Arthritis Receiving Methotrexate: A Single-center Retrospective Study.

Authors:  Shin-Ichiro Ohmura; Yoichiro Homma; Takayuki Masui; Toshiaki Miyamoto
Journal:  Intern Med       Date:  2021-09-11       Impact factor: 1.282

Review 3.  A risk-benefit assessment of slow-acting antirheumatic drugs in rheumatoid arthritis.

Authors:  A A Kalla; A F Tooke; E Bhettay; O L Meyers
Journal:  Drug Saf       Date:  1994-07       Impact factor: 5.606

4.  Incidence, mortality, and national costs of hospital admissions for potentially preventable infections in patients with rheumatoid arthritis.

Authors:  Joanna Potera; Soumyasri Kambhatla; Estefania Gauto-Mariotti; Augustine Manadan
Journal:  Clin Rheumatol       Date:  2021-07-12       Impact factor: 2.980

5.  Ramsay-Hunt syndrome complicating osteonecrosis of edentulous maxilla and mandible: report of a rare case.

Authors:  Samprati J Badjate; K M Cariappa; S R Shenoi; Shweta Nakhate
Journal:  J Maxillofac Oral Surg       Date:  2009-08-11

6.  Campylobacter jejuni arthritis in secondary amyloidosis.

Authors:  C H Simon; H M Markusse
Journal:  Clin Rheumatol       Date:  1995-03       Impact factor: 2.980
  6 in total

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