OBJECTIVE: To compare the resistance pattern of common bacterial pathogens to commonly used drugs. METHODS: Information and statistics of antimicrobial resistance for 1994 and 2005 were collected from the 3 hospital microbiology laboratories in the United Arab Emirates. The resistance patterns of Staphylococcus aureus, Escherichia coli, Klebsiella spp, and Pseudomonas aeruginosa to several front-line drugs were estimated. All laboratories used automatic machines (Vitek 2), which identifies and determines minimum inhibitory concentrations simultaneously. RESULTS: Increased resistance was observed for Staphylococcus aureus, (n=315, 2005) to erythromycin (approximately 6 fold, Al-Ain Hospital only), cloxacillin (Al-Ain Hospital), and gentamicin (more than 3-10 folds in all hospitals). Increased penicillin resistance was not observed. For the common gram-negative organisms, there was a high resistance to ampicillin, gentamicin, ceftriaxone, ciprofloxacin, and imipenem, which seemed to increase for Escherichia coli, (by 4.2-200%, n=305, 2005); however, there was very little resistance to imipenem (0.4%) in Tawam Hospital. Variable resistance patterns were obtained for Pseudomonas aeruginosa (n=316, 2005) and Klebsiella spp, (n=316, 2005) against aminoglycosides, cephalosporins, ciprofloxacin, and norfloxacin. CONCLUSION: Overall, there was an obvious increase in resistance of bacteria and the prevalence rate to a number of drugs from 1-120 folds during the 11-year period.
OBJECTIVE: To compare the resistance pattern of common bacterial pathogens to commonly used drugs. METHODS: Information and statistics of antimicrobial resistance for 1994 and 2005 were collected from the 3 hospital microbiology laboratories in the United Arab Emirates. The resistance patterns of Staphylococcus aureus, Escherichia coli, Klebsiella spp, and Pseudomonas aeruginosa to several front-line drugs were estimated. All laboratories used automatic machines (Vitek 2), which identifies and determines minimum inhibitory concentrations simultaneously. RESULTS: Increased resistance was observed for Staphylococcus aureus, (n=315, 2005) to erythromycin (approximately 6 fold, Al-Ain Hospital only), cloxacillin (Al-Ain Hospital), and gentamicin (more than 3-10 folds in all hospitals). Increased penicillin resistance was not observed. For the common gram-negative organisms, there was a high resistance to ampicillin, gentamicin, ceftriaxone, ciprofloxacin, and imipenem, which seemed to increase for Escherichia coli, (by 4.2-200%, n=305, 2005); however, there was very little resistance to imipenem (0.4%) in Tawam Hospital. Variable resistance patterns were obtained for Pseudomonas aeruginosa (n=316, 2005) and Klebsiella spp, (n=316, 2005) against aminoglycosides, cephalosporins, ciprofloxacin, and norfloxacin. CONCLUSION: Overall, there was an obvious increase in resistance of bacteria and the prevalence rate to a number of drugs from 1-120 folds during the 11-year period.
Authors: Khalid A Al-Kubaisi; Mark De Ste Croix; Don Vinson; Suleiman I Sharif; Abduelmula R Abduelkarem Journal: Pharm Pract (Granada) Date: 2018-06-27
Authors: Y K Wan; W Sang; B Chen; Y G Yang; L Q Zhang; A N Sun; Y J Liu; Y Xu; Y P Cai; C B Wang; Y F Shen; Y W Jiang; X Y Zhang; W Xu; M Hong; T Chen; R R Xu; F Li; Y L Xu; Y Xue; Y L Lu; Z M He; W M Dong; Z Chen; M H Ji; Y Y Yang; L J Zhai; Y Zhao; G Q Wu; J H Ding; J Cheng; W B Cai; Y M Sun; J Ouyang Journal: Zhonghua Xue Ye Xue Za Zhi Date: 2017-07-14
Authors: Ghada Elderdiri Abdelwahab; Hassan Zackaria Ali Ishag; Zulaikha Mohamed Al Hammadi; Saeed Mohamed S Al Yammahi; Mohd Faoruk Bin Mohd Yusof; Muna Sayed Y Al Yassi; Shaikha Saeed A Al Neyadi; Asma Mohammed A Al Mansoori; Fawzia Hassan A Al Hamadi; Ibtesam Abdullah S Al Hamadi; Mohamed Ali Abdalla Al Hosani; Salama Suhail Mohammed Al Muhairi Journal: Int J Microbiol Date: 2022-04-26