Conditioned place preference induced by morphine in non-copulating male rats.

Non-copulators (NC) are normal males that fail to display sexual behavior, we evaluate if NC male rats have a functional general reward system. NC male rats were injected with morphine to determine if a reward state, as evaluated by the conditioned place preference (CPP) paradigm, could be induced. Our results demonstrate that NC males develop CPP to a morphine injection, indicating that their general reward system is functional.