| Literature DB >> 19416710 |
Abstract
Osteoclasts are the primary cells that resorb bone; they require high energy levels to degrade bone matrix, releasing minerals to maintain calcium homeostasis. Recent work on osteoclast differentiation and activity highlights an important role for mitochondrial biogenesis and explores the role of iron transferrin in generating a positive osteoclastogenic feedback loop.Entities:
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Year: 2009 PMID： 19416710 DOI： 10.1016/j.cmet.2009.04.005
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287