Literature DB >> 19416225

A randomized, double-blind, placebo-controlled trial of relaxin for cervical ripening in post-delivery date pregnancies.

Gerson Weiss1, Sam Teichman, Dennis Stewart, David Nader, Susan Wood, Elaine Unemori.   

Abstract

Recombinant human relaxin was used to attempt cervical ripening in post-delivery date pregnancies. High doses of relaxin were safe but did not advance cervical ripening or induce labor.

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Year:  2009        PMID： 19416225     DOI： 10.1111/j.1749-6632.2008.03794.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  10 in total

Review 1.  Effects of relaxin on arterial dilation, remodeling, and mechanical properties.

Authors:  Kirk P Conrad; Sanjeev G Shroff
Journal:  Curr Hypertens Rep       Date:  2011-12       Impact factor: 5.369

2.  Relaxin modulates proinflammatory cytokine secretion from human decidual macrophages.

Authors:  J S Horton; S Y Yamamoto; G D Bryant-Greenwood
Journal:  Biol Reprod       Date:  2011-07-06       Impact factor: 4.285

Review 3.  Maternal vasodilation in pregnancy: the emerging role of relaxin.

Authors:  Kirk P Conrad
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2011-05-25       Impact factor: 3.619

Review 4.  Synthetic non-peptide low molecular weight agonists of the relaxin receptor 1.

Authors:  Alexander I Agoulnik; Irina U Agoulnik; Xin Hu; Juan Marugan
Journal:  Br J Pharmacol       Date:  2016-11-30       Impact factor: 8.739

5.  Relaxin-mediated renal vasodilation in the rat is associated with falls in glomerular blood pressure.

Authors:  Aihua Deng; Kirk Conrad; Chris Baylis
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2017-10-18       Impact factor: 3.619

Review 6.  International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides.

Authors:  Michelle L Halls; Ross A D Bathgate; Steve W Sutton; Thomas B Dschietzig; Roger J Summers
Journal:  Pharmacol Rev       Date:  2015       Impact factor: 25.468

Review 7.  Anti-fibrotic actions of relaxin.

Authors:  C S Samuel; S G Royce; T D Hewitson; K M Denton; T E Cooney; R G Bennett
Journal:  Br J Pharmacol       Date:  2016-07-07       Impact factor: 8.739

Review 8.  G-Protein-coupled receptors as potential drug candidates in preeclampsia: targeting the relaxin/insulin-like family peptide receptor 1 for treatment and prevention.

Authors:  Kirk P Conrad
Journal:  Hum Reprod Update       Date:  2016-07-06       Impact factor: 15.610

Review 9.  Relaxin for cervical ripening and induction of labour.

Authors:  A J Kelly; J Kavanagh; J Thomas
Journal:  Cochrane Database Syst Rev       Date:  2001

10.  Recombinant human relaxin versus placebo for cervical ripening: a double-blind randomised trial in pregnant women scheduled for induction of labour.

Authors:  Gerson Weiss; Sam Teichman; Dennis Stewart; David Nader; Susan Wood; Peter Breining; Elaine Unemori
Journal:  BMC Pregnancy Childbirth       Date:  2016-09-05       Impact factor: 3.007
  10 in total

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