| Literature DB >> 19415738 |
Bonnie J Nieves1, Patricia A D'Amore, Brad A Bryan.
Abstract
Vascular endothelial growth factor (VEGF) is considered the master regulator of angiogenesis during growth and development, as well as in disease states such as cancer, diabetes, and macular degeneration. This review details our current understanding of VEGF signaling and discusses the benefits and unexpected side effects of promising anti-angiogenic therapeutics that are currently being used to inhibit neovacularization in tumors.Entities:
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Year: 2009 PMID: 19415738 DOI: 10.1002/biof.46
Source DB: PubMed Journal: Biofactors ISSN: 0951-6433 Impact factor: 6.113