Literature DB >> 19415694

The x(c)(-) cystine/glutamate antiporter (xCT) as a potential target for therapy of cancer: yet another cytotoxic anticancer approach?

Nic E Savaskan, Eric Hahnen, Ilker Y Eyüpoglu.   

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Year:  2009        PMID： 19415694     DOI： 10.1002/jcp.21795

Source DB:  PubMed          Journal:  J Cell Physiol        ISSN： 0021-9541            Impact factor:   6.384


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  3 in total

1.  Histone deacetylases inhibition by SAHA/Vorinostat normalizes the glioma microenvironment via xCT equilibration.

Authors:  Ines M L Wolf; Zheng Fan; Manfred Rauh; Sebastian Seufert; Nirjhar Hore; Michael Buchfelder; Nic E Savaskan; Ilker Y Eyüpoglu
Journal:  Sci Rep       Date:  2014-09-17       Impact factor: 4.379

2.  Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema.

Authors:  Tina Sehm; Zheng Fan; Ali Ghoochani; Manfred Rauh; Tobias Engelhorn; Georgia Minakaki; Arnd Dörfler; Jochen Klucken; Michael Buchfelder; Ilker Y Eyüpoglu; Nicolai Savaskan
Journal:  Oncotarget       Date:  2016-06-14

3.  Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis.

Authors:  Tina Sehm; Manfred Rauh; Kurt Wiendieck; Michael Buchfelder; IIker Y Eyüpoglu; Nicolai E Savaskan
Journal:  Oncotarget       Date:  2016-11-15
  3 in total

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