Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Lon protease is essential for paradoxical survival of Escherichia coli exposed to high concentrations of quinolone.

Literature DB >> 19414573

Lon protease is essential for paradoxical survival of Escherichia coli exposed to high concentrations of quinolone.

Muhammad Malik¹, Joseph Capecci, Karl Drlica.

Abstract

A deficiency of the Escherichia coli Lon protease blocked paradoxical survival occurring at very high nalidixic acid concentrations. The absence of Lon also blocked a parallel increase in cell lysate viscosity likely to reflect DNA size. Thus, Lon may participate in repairing quinolone-mediated DNA lesions formed at high drug concentrations.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 2009 PMID： 19414573 PMCID： PMC2704693 DOI： 10.1128/AAC.00019-09

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

17 in total

1. DNA gyrase on the bacterial chromosome: DNA cleavage induced by oxolinic acid.

Authors: M Snyder; K Drlica
Journal: J Mol Biol Date: 1979-06-25 Impact factor: 5.469

2. A protease pathway for the repair of topoisomerase II-DNA covalent complexes.

Authors: Ailing Zhang; Yi Lisa Lyu; Chao-Po Lin; Nai Zhou; Anna M Azarova; Laurence M Wood; Leroy F Liu
Journal: J Biol Chem Date: 2006-09-13 Impact factor: 5.157

Review 3. Lex marks the spot: the virulent side of SOS and a closer look at the LexA regulon.

Authors: William L Kelley
Journal: Mol Microbiol Date: 2006-10-17 Impact factor: 3.501

4. Phage P1 mutants with altered transducing abilities for Escherichia coli.

Authors: J D Wall; P D Harriman
Journal: Virology Date: 1974-06 Impact factor: 3.616

5. Nalidixic acid: an antibacterial paradox.

Authors: G C Crumplin; J T Smith
Journal: Antimicrob Agents Chemother Date: 1975-09 Impact factor: 5.191

6. Prophage induction and cell division in E. coli. III. Mutations sfiA and sfiB restore division in tif and lon strains and permit the expression of mutator properties of tif.

Authors: J George; M Castellazzi; G Buttin
Journal: Mol Gen Genet Date: 1975-10-22

7. Escherichia coli DNA topoisomerase I mutants have compensatory mutations in DNA gyrase genes.

Authors: S DiNardo; K A Voelkel; R Sternglanz; A E Reynolds; A Wright
Journal: Cell Date: 1982-11 Impact factor: 41.582

8. Specificity of mutagenesis resulting from the induction of the SOS system in the absence of mutagenic treatment.

Authors: J H Miller; K B Low
Journal: Cell Date: 1984-06 Impact factor: 41.582

9. Second-site mutations in capR (lon) strains of Escherichia coli K-12 that prevent radiation sensitivity and allow bacteriophage lambda to lysogenize.

Authors: R C Gayda; L T Yamamoto; A Markovitz
Journal: J Bacteriol Date: 1976-09 Impact factor: 3.490

10. Mutations in the gene coding for Escherichia coli DNA topoisomerase I affect transcription and transposition.

Authors: R Sternglanz; S DiNardo; K A Voelkel; Y Nishimura; Y Hirota; K Becherer; L Zumstein; J C Wang
Journal: Proc Natl Acad Sci U S A Date: 1981-05 Impact factor: 11.205

8 in total

1. Suppression of Reactive Oxygen Species Accumulation Accounts for Paradoxical Bacterial Survival at High Quinolone Concentration.

Authors: Gan Luan; Yuzhi Hong; Karl Drlica; Xilin Zhao
Journal: Antimicrob Agents Chemother Date: 2018-02-23 Impact factor: 5.191

2. Escherichia coli genes that reduce the lethal effects of stress.

Authors: Xiulin Han; Angella Dorsey-Oresto; Muhammad Malik; Jian-Ying Wang; Karl Drlica; Xilin Zhao; Tao Lu
Journal: BMC Microbiol Date: 2010-02-04 Impact factor: 3.605

3. Fluoroquinolone-gyrase-DNA complexes: two modes of drug binding.

Authors: Arkady Mustaev; Muhammad Malik; Xilin Zhao; Natalia Kurepina; Gan Luan; Lisa M Oppegard; Hiroshi Hiasa; Kevin R Marks; Robert J Kerns; James M Berger; Karl Drlica
Journal: J Biol Chem Date: 2014-02-04 Impact factor: 5.157

Review 4. Toxin-Antitoxin Modules Are Pliable Switches Activated by Multiple Protease Pathways.

Authors: Meenakumari Muthuramalingam; John C White; Christina R Bourne
Journal: Toxins (Basel) Date: 2016-07-09 Impact factor: 4.546

5. A High-Throughput Screening Platform of Microbial Natural Products for the Discovery of Molecules with Antibiofilm Properties against Salmonella.

Authors: Sonia Paytubi; Mercedes de La Cruz; Jose R Tormo; Jesús Martín; Ignacio González; Victor González-Menendez; Olga Genilloud; Fernando Reyes; Francisca Vicente; Cristina Madrid; Carlos Balsalobre
Journal: Front Microbiol Date: 2017-03-02 Impact factor: 5.640